Peptides & Building Blocks

Myelin Oligodendrocyte Glycoprotein Peptide (35-55)

  • CAS No.149635-73-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity MOG (35-55) peptide for immunological research and EAE model development. Manufactured under strict GMP guidelines with COA provided.

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Product Technical Details

Product Overview

Our Myelin Oligodendrocyte Glycoprotein Peptide (35-55), commonly referred to as MOG (35-55), is a highly specialized research peptide designed for advanced immunological and neurological studies. This specific amino acid sequence represents the extracellular domain of the myelin oligodendrocyte glycoprotein, playing a critical role in the structural integrity of the central nervous system myelin sheath. As a premier manufacturer, we ensure that every batch meets rigorous purity standards suitable for sensitive experimental applications.

This product is extensively utilized in the induction of experimental autoimmune encephalomyelitis (EAE), a widely accepted animal model for studying multiple sclerosis pathogenesis. The peptide's ability to induce robust T cell and B cell responses makes it an invaluable tool for researchers investigating demyelinating diseases and autoimmune mechanisms. Our synthesis processes are optimized to maintain the structural integrity and biological activity required for consistent experimental outcomes.

Technical Specifications

We adhere to strict quality control protocols to guarantee the reliability of our chemical products. The following table outlines the key physical and chemical properties verified during our quality assurance process.

ParameterSpecification
CAS Number149635-73-4
Molecular FormulaC118H177N35O29S
Molecular Weight2581.950 g/mol
Purity (Assay)≥98.0%
AppearanceWhite to off-white powder
Density1.5±0.1 g/cm3
Index of Refraction1.678

Industrial Applications

The primary application of MOG (35-55) lies in biomedical research, specifically within the fields of neuroimmunology and pharmacology. It serves as a critical antigen for inducing autoimmune responses in preclinical models. Researchers utilize this peptide to evaluate potential therapeutic interventions aimed at mitigating neuroinflammation and demyelination. Due to its high encephalitogenic potential, it is essential for handling this material within appropriate laboratory settings equipped for biological safety.

  • Development of multiple sclerosis research models
  • Immunological assay standardization
  • Antibody production and epitope mapping
  • Studies on blood-brain barrier permeability
  • Evaluation of neuroprotective compounds

Quality Assurance and Storage

Each production lot undergoes comprehensive analytical testing, including HPLC and mass spectrometry, to confirm identity and purity. We provide a Certificate of Analysis (COA) with every shipment to ensure transparency and compliance with research standards. To maintain stability, the product should be stored in a cool, ventilated environment away from direct sunlight and moisture. Proper storage conditions are vital to preserve the peptide's biochemical properties over time.

We offer flexible packaging options, including standard 25 kg drums or customized solutions based on specific project requirements. Our global logistics network ensures timely delivery while maintaining the cold chain or protective packaging necessary for sensitive biochemical reagents. Partner with us for reliable supply chains and technical support in your research endeavors.