Peptides & Building Blocks

N-Acetyl-D-Alanine

  • CAS No.19436-52-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N-Acetyl-D-Alanine (CAS 19436-52-3) designed for pharmaceutical synthesis and peptide building applications with strict quality control.

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Product Technical Details

Product Overview

N-Acetyl-D-Alanine, identified by CAS number 19436-52-3, is a high-value chiral building block extensively utilized in the pharmaceutical and fine chemical industries. As a protected form of D-Alanine, this compound serves as a critical intermediate in the synthesis of complex peptides and specialized organic molecules. Our manufacturing process ensures exceptional stereochemical purity, making it an ideal choice for researchers and industrial producers requiring reliable raw materials for advanced synthesis pathways.

This acetylated amino acid derivative is characterized by its stability and reactivity, facilitating efficient coupling reactions in peptide chain elongation. The N-acetyl group provides necessary protection during multi-step synthesis, preventing unwanted side reactions while maintaining the integrity of the chiral center. Our facility adheres to rigorous quality management systems to guarantee consistency across every batch produced.

Chemical Properties and Specifications

The physical characteristics of N-Acetyl-D-Alanine are optimized for handling and processing in standard laboratory and industrial environments. The compound presents as a white crystalline powder with high solubility in common polar solvents, enabling versatile application in various reaction media. Strict control over physical parameters ensures compatibility with downstream processing requirements.

ParameterSpecification
CAS Number19436-52-3
Molecular FormulaC5H9NO3
Molecular Weight131.13 g/mol
AppearanceWhite crystalline powder
Purity (HPLC)≥98.0%
Water Content≤2.0%
Loss on Drying≤2.0%
Melting Point118.9-123.1°C

Quality Assurance and Testing

Quality is paramount in the production of pharmaceutical intermediates. Each batch of N-Acetyl-D-Alanine undergoes comprehensive analytical testing to verify identity and purity. Our quality control protocols include infrared spectroscopy (IR), mass spectrometry (MS), and nuclear magnetic resonance (NMR) for structural confirmation. High-performance liquid chromatography (HPLC) is employed to quantify purity levels, ensuring they meet or exceed the stated specification of 98 percent.

We provide a Certificate of Analysis (COA) with every shipment, detailing the specific test results for appearance, identification, purity, clarity of solution, water content, and loss on drying. This transparency allows our clients to integrate our materials into their supply chains with confidence, knowing that regulatory and performance standards are met consistently.

Industrial Applications

The primary application of this compound lies in the synthesis of pharmaceutical agents and peptide-based therapeutics. It serves as a fundamental building block for constructing larger biomolecules where chirality plays a crucial role in biological activity. Additionally, it is used in the development of specialized agrochemicals and fine chemicals where specific stereochemistry is required.

  • Peptide synthesis and modification
  • Pharmaceutical intermediate production
  • Chiral catalyst development
  • Research and development in organic chemistry

Storage and Handling

To maintain optimal stability, N-Acetyl-D-Alanine should be stored in a cool, dry environment at temperatures below -20°C. Containers must remain tightly closed to prevent moisture absorption, which could affect product quality. The material should be kept in a well-ventilated area away from incompatible substances. Proper handling procedures, including the use of personal protective equipment, are recommended during transfer and weighing operations to ensure safety and product integrity.