Peptides & Building Blocks

N-Acetyl-D-Leucine

  • CAS No.19764-30-8
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity N-Acetyl-D-Leucine (CAS 19764-30-8) supplied for pharmaceutical research and formulation. Certified quality with full COA available for global shipping.

Request a Quote & Full COA

Product Technical Details

Product Overview

N-Acetyl-D-Leucine, systematically known as (2R)-2-acetamido-4-methylpentanoic acid, represents a high-value chiral building block extensively utilized in advanced pharmaceutical synthesis and peptide chemistry. As a protected amino acid derivative, this compound offers exceptional stability and reactivity profiles, making it an indispensable component for researchers and manufacturers focused on neurological therapeutics and complex organic synthesis. Our facility specializes in the production of this fine chemical under strict quality control protocols to ensure consistency across large-scale batches.

We understand the critical nature of supply chain reliability in the pharmaceutical industry. Therefore, our manufacturing process adheres to international standards, providing a product that meets the rigorous demands of modern drug development. Whether used as a key intermediate in multi-step synthesis or as a functional ingredient in specialized formulations, this material delivers reliable performance and purity.

Technical Specifications

Quality is the cornerstone of our chemical supply operations. Each batch of N-Acetyl-D-Leucine undergoes comprehensive analytical testing to verify identity, purity, and physical properties. The following table outlines the standard specification parameters that define our premium grade material. Custom specifications may be available upon request for specific project requirements.

ParameterSpecification
CAS Number19764-30-8
Molecular FormulaC8H15NO3
Molecular Weight173.21 g/mol
AppearanceWhite to off-white powder
Purity (HPLC)≥99.0%
Melting Point176-177°C
Loss on Drying≤0.5%
Residue on Ignition≤0.3%

Industrial Applications

This acetylated amino acid derivative serves multiple roles within the chemical and pharmaceutical sectors. Its primary application lies in the synthesis of peptide-based therapeutics where chiral integrity is paramount. The N-acetyl protection group ensures stability during coupling reactions, preventing unwanted side reactions and facilitating smoother synthesis pathways. Additionally, due to its specific stereochemistry, it is employed in the development of formulations targeting neurological support and vestibular function.

  • Pharmaceutical Intermediate: Used in the synthesis of active pharmaceutical ingredients requiring D-leucine scaffolds.
  • Peptide Synthesis: Acts as a reliable building block for constructing complex peptide chains with high stereochemical purity.
  • Research and Development: Essential for laboratories investigating neurological therapeutics and metabolic pathways.
  • Formulation Component: Suitable for inclusion in specialized health and wellness formulations requiring amino acid derivatives.

Quality Assurance And Storage

To maintain the integrity of N-Acetyl-D-Leucine, proper storage conditions are essential. The material should be kept in a tightly closed container within a cool, dry environment, ideally at temperatures around -20°C for long-term stability. Exposure to moisture or excessive heat should be avoided to prevent degradation. We package our products in 25 kg drums as standard, with flexible packaging options available to suit logistical needs. Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications. Our commitment to safety and quality ensures that partners receive a product ready for immediate integration into their production processes.