Peptides & Building Blocks

N-Acetyl-L-Valine

  • CAS No.96-81-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity N-Acetyl-L-Valine (CAS 96-81-1) designed for pharmaceutical synthesis and peptide building applications with strict quality control.

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Product Technical Details

Product Overview

N-Acetyl-L-Valine is a critically important protected amino acid derivative widely utilized in the field of organic synthesis and medicinal chemistry. As a key building block, this compound features an acetyl group protecting the amine functionality of the essential amino acid L-Valine. This protection strategy is vital for controlling reactivity during complex multi-step synthesis processes, particularly in the construction of peptide chains and modified protein structures. Our manufacturing process ensures high optical purity, maintaining the specific L-configuration required for biological activity and stereochemical consistency in downstream applications.

The compound is characterized by its stability and solubility profile, making it an ideal candidate for solid-phase peptide synthesis (SPPS) and solution-phase coupling reactions. By preventing unwanted side reactions at the amino group, N-Acetyl-L-Valine allows chemists to achieve higher yields and greater specificity in the production of advanced pharmaceutical intermediates. We adhere to stringent production standards to guarantee that every batch meets the rigorous demands of research and industrial scale-up.

Technical Specifications

ParameterSpecification
CAS Number96-81-1
Molecular FormulaC7H13NO3
Molecular Weight159.18 g/mol
AppearanceWhite to off-white powder or crystals
Purity (HPLC)≥98.0%
Heavy Metals (Pb)≤20 ppm
Loss on Drying≤2.0%
Residue on Ignition≤0.50%

Industrial Applications

The primary application of N-Acetyl-L-Valine lies within the pharmaceutical and biotechnology sectors. It serves as a fundamental intermediate in the synthesis of various peptide-based therapeutics, including hormones, enzymes, and novel drug candidates. The acetyl protection group is particularly useful when valine residues need to be incorporated into a peptide sequence without participating in unintended coupling reactions at the N-terminus. Additionally, this compound is utilized in the development of nutraceuticals and specialized dietary supplements where specific amino acid profiles are required.

Beyond direct peptide synthesis, this chemical finds utility in the creation of peptidomimetics and small molecule drugs that target specific biological pathways. Its high purity ensures that final products meet regulatory compliance standards for safety and efficacy. Researchers value this material for its consistent performance in coupling reactions, reducing the need for extensive purification steps later in the synthesis workflow.

Quality Assurance and Storage

Quality is paramount in the production of fine chemicals and pharmaceutical intermediates. Each batch of N-Acetyl-L-Valine undergoes comprehensive analytical testing, including HPLC analysis, melting point determination, and spectral verification to confirm identity and purity. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international quality standards. Our facility operates under strict environmental controls to prevent contamination and maintain product integrity.

Proper storage is essential to maintain the stability of this compound. It should be kept in tightly closed containers in a cool, dry environment, ideally at temperatures around -20ºC for long-term preservation. The material is sensitive to moisture and should be protected from humidity to prevent hydrolysis of the amide bond. We offer flexible packaging options, including standard 25 kg drums, and can accommodate custom packaging requirements to suit specific logistical needs for global distribution.