Nα-benzyloxycarbonylvalyltyrosine

Product Overview

Nα-benzyloxycarbonylvalyltyrosine, commonly known by its shorthand notation Z-Val-Tyr-OH, represents a critical protected dipeptide intermediate within the realm of advanced organic synthesis and peptide chemistry. This compound features a valine residue linked to a tyrosine residue, with the N-terminus protected by a benzyloxycarbonyl (Cbz or Z) group. This specific protection strategy is essential for preventing unwanted side reactions during chain elongation processes, ensuring high fidelity in the construction of complex peptide structures.

As a foundational building block, this material is extensively utilized in the development of pharmaceutical active ingredients, diagnostic peptides, and research-grade biomolecules. Our manufacturing process adheres to strict quality control protocols to deliver consistent batch-to-batch reliability, making it an ideal choice for both laboratory-scale research and large-scale production environments.

Technical Specifications

We maintain rigorous standards for all chemical intermediates to ensure they meet the demanding requirements of modern synthesis workflows. The following table outlines the key physical and chemical properties of this product:

Applications in Peptide Chemistry

The primary utility of Nα-benzyloxycarbonylvalyltyrosine lies in its role as a versatile intermediate for peptide synthesis. The presence of the Cbz protecting group allows for selective deprotection under specific conditions, facilitating controlled coupling reactions. This is particularly valuable in solution-phase synthesis where orthogonal protection strategies are required.

• Pharmaceutical Intermediate: Used in the synthesis of peptide-based drugs and therapeutic candidates.
• Research and Development: Essential for constructing model peptides to study structure-activity relationships.
• Custom Synthesis: Serves as a key fragment for producing longer peptide sequences with high optical purity.

Its stability under standard handling conditions makes it suitable for various industrial processes, ensuring that the integrity of the chiral centers is maintained throughout the synthesis route.

Quality Assurance and Storage

Quality is paramount in the production of fine chemicals. Each batch of Nα-benzyloxycarbonylvalyltyrosine undergoes comprehensive analytical testing, including HPLC and NMR spectroscopy, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to document compliance with specifications.

Proper storage is crucial to maintain product stability. We recommend storing the material at -15ºC in a tightly closed container. The environment should be cool, dry, and well-ventilated to prevent moisture absorption or degradation. Keeping the container sealed when not in use ensures prolonged shelf life and consistent performance in downstream applications.

Why Partner With Us

As a global manufacturer with decades of experience in the pharmaceutical chemical industry, we are committed to supplying high-quality intermediates that drive innovation. Our supply chain is optimized for reliability, offering competitive bulk pricing and flexible packaging options to suit diverse customer requirements. Whether you need small quantities for research or metric tons for production, our team is dedicated to supporting your project goals with technical expertise and logistical efficiency.