N-Boc-D-cyclohexylglycinol
- CAS No.188348-00-7
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-Boc-D-cyclohexylglycinol (CAS 188348-00-7) is a premium chiral building block designed for pharmaceutical synthesis. We offer bulk quantities with strict quality control and comprehensive COA documentation.
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Product Overview
N-Boc-D-cyclohexylglycinol represents a critical chiral building block within the realm of advanced organic synthesis and pharmaceutical development. Identified by CAS number 188348-00-7, this protected amino alcohol derivative serves as a foundational component for constructing complex molecular architectures. The presence of the tert-butyloxycarbonyl (Boc) protecting group ensures stability during multi-step synthesis routes, while the cyclohexyl moiety introduces specific steric and electronic properties essential for targeted biological activity.
Our manufacturing process adheres to rigorous international standards, guaranteeing consistent quality across every batch. This compound is particularly valued in the creation of peptidomimetics and specialized pharmaceutical intermediates where stereochemical integrity is paramount. By utilizing high-grade raw materials and optimized purification techniques, we deliver a product that meets the demanding specifications required by modern medicinal chemistry laboratories.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | tert-butyl N-[(1R)-1-cyclohexyl-2-hydroxyethyl]carbamate |
| CAS Number | 188348-00-7 |
| Molecular Formula | C13H25NO3 |
| Molecular Weight | 243.34 g/mol |
| Appearance | White powder |
| Purity | ≥98% |
| Melting Point | 83-87°C |
| Density | 1.037 g/cm3 |
| Boiling Point | 371.2°C at 760 mmHg |
| Flash Point | 178.3°C |
| Refractive Index | 1.482 |
Industrial Applications
This chiral intermediate finds extensive application in the synthesis of bioactive compounds and therapeutic agents. Its primary utility lies in peptide synthesis, where it acts as a protected amino acid equivalent. The D-configuration provides access to specific stereoisomers that are often required to enhance metabolic stability or receptor binding affinity in drug candidates. Furthermore, the hydroxyl group allows for further functionalization, enabling chemists to introduce diverse chemical handles for downstream modifications.
- Pharmaceutical intermediate for novel drug discovery
- Building block for peptidomimetic structures
- Chiral auxiliary in asymmetric synthesis
- Component in specialized polymer formulations
Quality Assurance and Storage
Maintaining the integrity of sensitive chemical building blocks is essential for reproducible research outcomes. Each shipment of N-Boc-D-cyclohexylglycinol is accompanied by a comprehensive Certificate of Analysis (COA), verifying identity, purity, and physical constants. We recommend storing this material at controlled temperatures between 0-5°C to prevent degradation. Containers should remain tightly closed in a cool, dry environment away from direct sunlight and moisture. Our packaging options include 25 kg drums, with custom solutions available to meet specific logistical requirements for global distribution.
