Peptides & Building Blocks

N-Boc-glycine Ethyl Ester

  • CAS No.14719-37-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade N-Boc-glycine Ethyl Ester designed for efficient peptide synthesis and pharmaceutical intermediate applications with guaranteed purity.

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Product Technical Details

Product Overview

N-Boc-glycine Ethyl Ester represents a critical protected amino acid derivative extensively utilized in modern organic synthesis and pharmaceutical development. As a stable glycine building block, this compound features a tert-butoxycarbonyl (Boc) protecting group on the nitrogen atom, which ensures compatibility with various reaction conditions while preventing unwanted side reactions during peptide chain elongation. Our manufacturing process adheres to strict quality control protocols to deliver consistent molecular integrity suitable for complex synthetic pathways.

This esterified form of glycine offers enhanced solubility in common organic solvents, facilitating smoother reaction kinetics in solution-phase peptide synthesis. The robust stability of the Boc group allows for selective deprotection under acidic conditions, providing chemists with precise control over synthetic sequences. Whether employed in the production of active pharmaceutical ingredients or specialized research compounds, this material serves as a foundational component for high-value chemical architectures.

Technical Specifications

ParameterSpecification
Chemical NameN-Boc-glycine Ethyl Ester
CAS Registry Number14719-37-0
Molecular FormulaC9H17NO4
Molecular Weight203.24 g/mol
AppearanceColorless to yellowish clear liquid
Purity≥99.0%
Density1.053 g/cm3
Boiling Point284°C at 760 mmHg
Flash Point125.5°C
Refractive Index1.44

Industrial Applications

The primary utility of N-Boc-glycine Ethyl Ester lies in its role as a versatile intermediate for the pharmaceutical and biotechnology sectors. It is predominantly employed in the construction of peptide-based therapeutics, where glycine residues are required within the primary sequence. The ethyl ester functionality provides a convenient handle for further modification, such as amidation or reduction, enabling diverse downstream transformations.

  • Peptide Synthesis: Acts as a reliable building block for solid-phase and solution-phase peptide assembly.
  • Pharmaceutical Intermediates: Serves as a key precursor in the manufacturing of complex drug molecules.
  • Organic Chemistry Research: Utilized in method development for amino acid functionalization and protection strategies.
  • Custom Synthesis: Available for bespoke chemical projects requiring high-purity protected amino acid derivatives.

Quality Assurance and Storage

We maintain rigorous quality assurance standards to ensure every batch meets the specified purity profiles. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) detailing test results against established parameters. To maintain optimal stability, the product should be stored in tightly closed containers at room temperature, away from moisture and direct light. Proper handling ensures the longevity of the protecting group and prevents hydrolysis of the ester functionality.

Our packaging options include standard 25 kg drums, with flexibility to accommodate specific customer requirements for bulk orders. As a global manufacturer, we prioritize safe logistics and timely delivery to support continuous production schedules worldwide. For technical inquiries or volume pricing, our sales team is ready to provide detailed support and documentation.