N-Boc-S-acetamidomethyl-L-cysteine

Product Overview

N-Boc-S-acetamidomethyl-L-cysteine, frequently recognized by its abbreviation Boc-Cys(Acm)-OH, stands as a critical protected amino acid derivative within the realm of pharmaceutical synthesis and peptide chemistry. This compound features a tert-butoxycarbonyl (Boc) group protecting the alpha-amino function and an acetamidomethyl (Acm) group safeguarding the thiol side chain of the cysteine residue. Such dual protection strategy is essential for preventing unwanted oxidation and side reactions during complex multi-step peptide assembly processes.

Our manufacturing facility ensures that every batch of this chemical building block meets rigorous international standards. The substance is primarily utilized in the solid-phase and solution-phase synthesis of biologically active peptides, where the integrity of the cysteine thiol group is paramount for maintaining the final product's structural stability and biological activity.

Technical Specifications

Industrial Applications

This protected cysteine derivative serves as a fundamental building block in the production of therapeutic peptides and protein mimetics. The Acm protecting group is particularly valued for its stability under acidic conditions used for Boc deprotection, while remaining removable under specific mild oxidative conditions or mercury treatment when free thiol functionality is required for disulfide bond formation.

• Pharmaceutical intermediate for hormone synthesis.
• Key reagent in custom peptide manufacturing.
• Research grade material for biochemical studies.
• Precursor for enzyme inhibitors and active pharmaceutical ingredients.

Quality Assurance and Storage

We prioritize quality control throughout the manufacturing process. Each shipment is accompanied by a Certificate of Analysis (COA) verifying purity, identity, and physical constants. To maintain optimal stability, the product should be stored in a tightly closed container at temperatures around -20ºC. It is imperative to keep the material in a cool, dry environment away from moisture and strong oxidizing agents. Proper handling ensures the longevity and reactivity of the building block for your synthesis projects.

For large-scale industrial requirements, we offer flexible packaging options, including standard 25 kg drums or customized solutions based on specific client logistics. Our global supply chain ensures timely delivery while maintaining the cold chain integrity necessary for sensitive amino acid derivatives.