N'-Cbz-L-lysine tert-butyl ester hydrochloride
- CAS No.5978-22-3
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity protected amino acid derivative designed for efficient peptide synthesis and pharmaceutical intermediate applications.
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Product Overview
N'-Cbz-L-lysine tert-butyl ester hydrochloride represents a critical protected amino acid derivative utilized extensively in modern organic synthesis and peptide chemistry. This compound features a carboxybenzyl (Cbz) protecting group on the epsilon-amino side chain and a tert-butyl ester protection on the carboxyl terminus, providing orthogonal stability during complex multi-step synthesis reactions. As a key building block, it enables chemists to construct sophisticated peptide sequences with high fidelity and minimal side reactions.
Our manufacturing process adheres to strict quality control standards, ensuring that each batch meets rigorous pharmaceutical-grade specifications. The hydrochloride salt form enhances stability and solubility in various organic solvents, making it an ideal candidate for both solution-phase and solid-phase peptide synthesis (SPPS) protocols. We prioritize consistency and purity to support research and development teams in accelerating their drug discovery pipelines.
Chemical Specifications
| Parameter | Specification |
|---|---|
| Chemical Name | N'-Cbz-L-lysine tert-butyl ester hydrochloride |
| CAS Number | 5978-22-3 |
| Molecular Formula | C18H29ClN2O4 |
| Molecular Weight | 372.89 g/mol |
| Appearance | White Crystalline Powder |
| Purity (HPLC) | ≥98.0% |
| Loss on Drying | ≤0.20% |
| Residue on Ignition | ≤0.10% |
Industrial Applications
This protected lysine derivative serves as a fundamental intermediate in the production of therapeutic peptides, diagnostic agents, and biochemical research tools. The orthogonal protection strategy allows for selective deprotection steps, enabling the precise assembly of amino acid sequences required for bioactive molecules. It is frequently employed in the synthesis of hormone analogs, enzyme inhibitors, and specialized ligands used in medicinal chemistry.
Beyond pharmaceutical applications, this compound supports the development of advanced materials and cosmetic peptides where specific amino acid sequences are required to achieve desired biological functions. Our global supply chain ensures that research laboratories and manufacturing facilities receive timely deliveries accompanied by comprehensive Certificates of Analysis (COA) and technical documentation.
Storage and Handling
To maintain optimal chemical integrity, N'-Cbz-L-lysine tert-butyl ester hydrochloride should be stored in a cool, dry environment at temperatures below -15°C. The product must be protected from light and moisture to prevent hydrolysis or degradation of the protecting groups. Containers should remain tightly sealed when not in use. We offer flexible packaging options, including 25 kg drums, customized to meet specific logistical requirements and ensure safe global transportation.
