N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline
- CAS No.16357-59-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High purity N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ) CAS 16357-59-8. Premium coupling reagent for peptide and organic synthesis applications.
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Product Overview
N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline, commonly known as EEDQ, is a highly efficient coupling reagent widely utilized in modern organic synthesis and peptide chemistry. As a specialized chemical intermediate, it facilitates the formation of amide bonds with exceptional reliability and minimal racemization. Our manufacturing process ensures consistent quality, making it an ideal choice for research laboratories and industrial-scale production facilities requiring precise chemical transformations.
This compound is characterized by its stability and reactivity profile, which allows for smooth condensation reactions under mild conditions. The molecular structure supports its function as a activating agent, enabling chemists to achieve high yields in complex synthesis routes. We adhere to strict quality control standards to guarantee that every batch meets the specified purity requirements for demanding applications.
Technical Specifications
| Parameter | Value |
|---|---|
| Chemical Name | N-Ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline |
| CAS Number | 16357-59-8 |
| Molecular Formula | C14H17NO3 |
| Molecular Weight | 247.29 g/mol |
| Appearance | Off-white to white crystalline powder |
| Purity (HPLC) | ≥99.0% |
| Melting Point | 62-67°C |
| Boiling Point | 125-128°C |
| Density | 1.16 g/cm³ |
| Refractive Index | 1.564 |
Industrial Applications
EEDQ serves as a critical component in the synthesis of pharmaceutical intermediates and fine chemicals. Its primary function lies in peptide coupling, where it activates carboxylic acids for nucleophilic attack by amines. This capability is essential for constructing peptide chains and modifying organic molecules with high precision. Additionally, it is employed in the preparation of various heterocyclic compounds and functionalized materials.
The reagent is compatible with a wide range of solvents and reaction conditions, offering flexibility in process development. Users benefit from its ability to minimize side reactions, thereby simplifying purification steps and improving overall process efficiency. Whether used in small-scale discovery or large-scale manufacturing, this product delivers consistent performance aligned with industry benchmarks.
Safety and Handling
Proper handling procedures are essential when working with this chemical substance. It is classified under Hazard Class 8 with UN Number 3265, indicating corrosive properties that require appropriate personal protective equipment. Storage should be maintained in a cool, ventilated area away from incompatible materials such as strong oxidizing agents. Containers must remain tightly sealed to prevent moisture absorption, which could affect product stability.
We provide comprehensive safety data sheets and certificates of analysis with every shipment to ensure compliance with global regulatory standards. Our packaging options include 25 kg drums, with custom configurations available upon request to suit specific logistical needs. For further technical support or bulk pricing inquiries, our team is ready to assist with detailed documentation and timely responses.
