N-Methyl-N-Cbz-D-alanine
- CAS No.68223-03-0
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-Methyl-N-Cbz-D-alanine for advanced peptide synthesis. Reliable supply with COA.
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Product Overview
N-Methyl-N-Cbz-D-alanine is a specialized protected amino acid derivative designed for sophisticated pharmaceutical and biochemical applications. As a key building block in organic synthesis, this compound features a D-alanine backbone protected by a Carboxybenzyl (Cbz) group on the nitrogen, along with an N-methyl substitution. This specific structural configuration enhances metabolic stability and conformational restriction when incorporated into peptide chains, making it invaluable for the development of novel therapeutic agents.
Our manufacturing process ensures exceptional chemical integrity and stereochemical purity. The compound is synthesized under strict quality control protocols to meet the rigorous demands of modern drug discovery and process chemistry. Whether used in solid-phase peptide synthesis or solution-phase methodologies, this reagent provides consistent performance and reliability.
Key Specifications
| Parameter | Value |
|---|---|
| CAS Number | 68223-03-0 |
| Molecular Formula | C12H15NO4 |
| Molecular Weight | 237.252 |
| Appearance | White powder |
| Assay | ≥98.0% |
| Density | 1.2±0.1 g/cm3 |
| Boiling Point | 389.5±31.0 °C at 760 mmHg |
| Flash Point | 189.4±24.8 °C |
Industrial Applications
This protected amino acid serves primarily as a critical intermediate in the synthesis of bioactive peptides and peptidomimetics. The N-methylation of the amino group is a strategic modification used to improve the pharmacokinetic properties of peptide drugs, such as enhancing membrane permeability and resistance to enzymatic degradation. Consequently, N-Methyl-N-Cbz-D-alanine is frequently employed in the research and development of antiviral, anticancer, and immunomodulatory compounds.
Furthermore, the Cbz protecting group offers excellent stability under various reaction conditions while remaining removable via hydrogenolysis or acid treatment when necessary. This versatility allows chemists to incorporate this building block into complex molecular architectures without compromising the integrity of surrounding functional groups. It is an essential reagent for laboratories focused on structure-activity relationship studies and lead optimization.
Quality Assurance and Storage
We are committed to delivering products that meet international quality standards. Each batch of N-Methyl-N-Cbz-D-alanine undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to verify identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality systems.
- Packaged in 25kg drums or customized according to client requirements.
- Store in a cool, dry, and well-ventilated area away from direct sunlight.
- Keep containers tightly closed to prevent moisture absorption and contamination.
- Handle with appropriate personal protective equipment during laboratory operations.
Our global logistics network ensures timely delivery while maintaining product stability during transit. For large-scale production needs, we offer competitive bulk pricing and dedicated technical support to assist with process scaling and integration.
