Peptides & Building Blocks

N-Z-L-Serine Methyl Ester

  • CAS No.1676-81-9
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity N-Z-L-Serine Methyl Ester (CAS 1676-81-9) designed for pharmaceutical synthesis and peptide building block applications.

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Product Technical Details

Product Overview

N-Z-L-Serine Methyl Ester, frequently recognized in the industry as Cbz-L-Serine Methyl Ester, stands as a critical protected amino acid derivative within the realm of advanced organic synthesis. This compound features a benzyloxycarbonyl (Z or Cbz) protecting group on the amine functionality and a methyl ester on the carboxyl group, rendering it an indispensable building block for peptide chemists and pharmaceutical researchers. Our facility specializes in the production of this high-value intermediate, ensuring consistent quality for complex molecular assembly.

The strategic protection of the serine side chain and amino group allows for selective reactions during multi-step synthesis protocols. This specificity is vital when constructing biologically active peptides or small molecule therapeutics where stereochemistry and functional group tolerance are paramount. We adhere to strict manufacturing standards to deliver a product that meets the rigorous demands of modern drug discovery pipelines.

Specifications and Physical Properties

Quality control is the cornerstone of our production process. Each batch of N-Z-L-Serine Methyl Ester undergoes comprehensive analytical testing to verify identity, purity, and physical characteristics. The following table outlines the key technical specifications associated with CAS 1676-81-9:

ParameterSpecification
CAS Number1676-81-9
Molecular FormulaC12H15NO5
Molecular Weight253.25 g/mol
AppearanceWhite or off-white solid
Purity≥99.0%
Water Content≤0.5%
Melting Point41-43 °C
Density1.254 g/cm3

These parameters ensure that the material performs predictably in downstream reactions, minimizing impurities that could affect yield or complicate purification processes.

Industrial Applications

This protected serine derivative serves multiple roles in the chemical and pharmaceutical sectors. Primarily, it is utilized as a key intermediate in the synthesis of peptide-based pharmaceuticals. The Z protecting group is stable under many conditions but can be removed selectively via hydrogenolysis, offering flexibility in synthetic route design.

Furthermore, research indicates utility in the development of compounds targeting specific biological pathways. It has been employed in studies related to the synthesis of pyrazinecarboxamide-based structures, which are investigated for their potential inhibitory activities against certain enzymes. Such applications highlight its versatility in creating novel therapeutic agents for metabolic and infectious disease research.

Storage and Handling

To maintain optimal stability and purity, proper storage conditions are essential. N-Z-L-Serine Methyl Ester should be stored in a cool, dry environment, ideally at temperatures around -15°C. Containers must remain tightly closed to prevent moisture absorption, which could lead to hydrolysis of the ester functionality. We recommend handling this material in a well-ventilated area using appropriate personal protective equipment. Our packaging options include 25 kg drums, with customization available to suit specific logistical requirements for global shipment.