Nα-tert-Butoxycarbonyl-L-asparagine

Product Overview

Nα-tert-Butoxycarbonyl-L-asparagine, commonly known as Boc-L-Asn-OH, is a critically important protected amino acid derivative utilized extensively in the field of organic synthesis and peptide chemistry. As a key building block, this compound features an N-terminal Boc protecting group that ensures stability during complex multi-step synthesis reactions. Our manufacturing process adheres to strict quality control standards, delivering a product suitable for high-level pharmaceutical research and development.

This protected form of L-asparagine is essential for preventing unwanted side reactions during peptide chain elongation. The tert-butoxycarbonyl group provides robust protection under various conditions while allowing for selective deprotection when required. This balance makes it a preferred choice for chemists working on novel therapeutic peptides and biochemical probes.

Technical Specifications

Physical and Chemical Properties

The compound exhibits stable physical characteristics suitable for long-term storage and handling in laboratory environments. With a density of approximately 1.253 g/cm³ and a high boiling point, it maintains integrity under standard processing conditions. The refractive index and flash point data further confirm its suitability for safe industrial handling when proper protocols are followed.

Quality consistency is paramount in peptide synthesis. Our production batches undergo rigorous analytical testing to ensure that impurities are minimized. This high level of purity is crucial for preventing sequence errors or side products in final peptide structures, which could compromise biological activity or research outcomes.

Industrial Applications

Primarily, this chemical serves as a fundamental intermediate in the synthesis of complex peptides and proteins. It is widely used in the development of pharmaceutical candidates where specific amino acid sequences are required. Additionally, it finds application in the creation of biochemical reagents and diagnostic tools.

• Solid-phase peptide synthesis (SPPS)
• Solution-phase peptide coupling
• Pharmaceutical intermediate production
• Biochemical research and development

Storage and Handling

To maintain optimal quality, Nα-tert-Butoxycarbonyl-L-asparagine should be stored in a cool, dry environment at temperatures around -20°C. Containers must remain tightly closed to prevent moisture absorption, which could affect purity levels over time. We recommend using inert atmosphere conditions during handling for sensitive applications.

Packaging is available in 25 kg drums as standard, with customization options available to meet specific logistical requirements. Each shipment includes a comprehensive Certificate of Analysis (COA) to verify compliance with stated specifications. Our global supply chain ensures timely delivery for research and manufacturing needs worldwide.