O-tert-Butyl-D-serine Methyl Ester Hydrochloride

Product Overview

O-tert-Butyl-D-serine Methyl Ester Hydrochloride is a specialized protected amino acid derivative designed for use in complex organic synthesis and pharmaceutical research. This compound features a tert-butyl protection group on the hydroxyl side chain and a methyl ester on the carboxyl terminus, making it an essential building block for the construction of stereochemically defined peptides. Our manufacturing process ensures high optical purity and consistent quality, meeting the rigorous demands of modern drug discovery and development pipelines.

As a key intermediate, this substance facilitates the efficient assembly of peptide sequences where serine residues require side-chain protection to prevent unwanted side reactions during coupling steps. The hydrochloride salt form enhances stability and solubility in various reaction conditions, providing chemists with a reliable reagent for solid-phase and solution-phase synthesis.

Key Specifications

Industrial Applications

This protected amino acid ester is primarily utilized in the pharmaceutical and biotechnology sectors. It serves as a critical precursor in the synthesis of therapeutic peptides, peptidomimetics, and specialized protein modifiers. The D-configuration offers unique structural properties required for specific biological activities or enzymatic stability in final drug products.

• Peptide drug development and optimization
• Construction of chiral libraries for screening
• Synthesis of enzyme inhibitors and substrates
• Research into novel antibiotic structures

Quality Assurance and Storage

Quality is paramount in our production facility. Each batch undergoes strict analytical testing using HPLC and NMR to verify identity, purity, and stereochemistry. We provide a comprehensive Certificate of Analysis (COA) with every shipment to ensure compliance with your internal quality standards. Proper storage is essential to maintain product integrity. We recommend keeping the container tightly closed in a cool, dry environment at 2-8ºC. Avoid exposure to moisture and strong oxidizing agents. Our packaging options include 25 kg drums or customized solutions based on specific client requirements, ensuring safe global transportation.