Peptides & Building Blocks

Thymidine-5'-monophosphate disodium salt

  • CAS No.33430-62-5
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Thymidine-5'-monophosphate disodium salt for biochemical synthesis and kinase assays. Reliable supply with full documentation.

Request a Quote & Full COA

Product Technical Details

Product Overview

Thymidine-5'-monophosphate disodium salt is a critical nucleotide derivative extensively utilized in biochemical research and pharmaceutical development. As a stable disodium salt form of thymidylic acid, this compound offers enhanced solubility and handling characteristics compared to its free acid counterpart. Our manufacturing process ensures exceptional consistency, making it an ideal choice for laboratories requiring reliable reagents for enzymatic studies and nucleic acid synthesis.

This nucleoside monophosphate serves as a fundamental building block in the biosynthesis of DNA. It is specifically designed to meet the rigorous demands of modern molecular biology, providing a high-quality substrate for various kinase-mediated reactions. The disodium formulation guarantees optimal stability during storage and transportation, preserving the integrity of the chemical structure until it is ready for use in sensitive experimental protocols.

Technical Specifications

ParameterSpecification
Chemical NameThymidine-5'-monophosphate disodium salt
CAS Number33430-62-5
Molecular FormulaC10H13N2Na2O8P
Molecular Weight366.17 g/mol
AppearanceWhite to off-white crystalline powder
Assay (HPLC)≥99.0%
Moisture Content≤13.0%
Melting Point>300°C

Applications and Benefits

The primary application of this compound lies in its role as a substrate for thymidylate kinase (TMPK), facilitating the preparation of thymidine diphosphate. This reaction is pivotal in understanding nucleotide metabolism and developing antiviral or anticancer therapeutics targeting DNA replication pathways. Furthermore, it acts as a constituent material for deoxyribonucleic acid, making it indispensable for oligonucleotide synthesis and genetic research.

  • High purity ensures minimal interference in enzymatic assays.
  • Stable disodium salt form enhances shelf life and handling safety.
  • Verified by HPLC to meet stringent pharmaceutical standards.
  • Ideal for use in kinase activity studies and DNA polymerization.
  • Supported by comprehensive quality documentation including COA.

Quality Assurance and Storage

Our facility adheres to strict quality control protocols to guarantee the purity and performance of every batch. Each production lot undergoes rigorous testing using high-performance liquid chromatography (HPLC) to confirm assay levels and identify impurities. We provide a Certificate of Analysis (COA) with every shipment, ensuring full traceability and compliance with international chemical safety standards.

To maintain optimal quality, store this product in a cool, ventilated area away from direct sunlight and moisture. The compound should be kept in tightly sealed containers to prevent hygroscopic absorption, which could affect its physical properties. Standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical requirements for global distribution.