Z-Arg(Pbf)-OH Cyclohexylamine Salt

Product Overview

Z-Arg(Pbf)-OH Cyclohexylamine Salt represents a critical protected amino acid derivative utilized extensively in the field of solid-phase peptide synthesis (SPPS) and solution-phase peptide construction. As a specialized building block, this compound features a Z (Benzyloxycarbonyl) protecting group on the alpha-amino function and a Pbf (2,2,4,6,7-pentamethyl-dihydrobenzofuran-5-sulfonyl) group on the guanidine side chain. This specific protection strategy ensures exceptional stability against racemization during coupling reactions while allowing for clean deprotection under acidic conditions. Our manufacturing process adheres to strict quality control protocols to deliver a reagent suitable for demanding pharmaceutical and biotechnological workflows.

Chemical Specifications

The following table outlines the key physicochemical properties and quality standards associated with this batch of Z-Arg(Pbf)-OH Cyclohexylamine Salt. Each production lot is accompanied by a comprehensive Certificate of Analysis (COA) to verify compliance with these specifications.

Industrial Applications

This protected amino acid salt serves as a fundamental precursor in the synthesis of complex peptide sequences, including therapeutic peptides and bioactive compounds. The Pbf group is particularly valued for its ability to suppress side reactions during the assembly of arginine-containing peptides, ensuring high final yields and purity. While primarily utilized in research and development for pharmaceutical intermediates, high-grade batches may also support the production of specialized cosmetic peptides or nutraceutical formulations where specific amino acid sequences are required. The cyclohexylamine salt form enhances solubility in organic solvents commonly used in peptide coupling, such as DMF and DCM, facilitating smoother reaction kinetics.

Quality Assurance and Handling

We maintain a robust quality management system to ensure the consistency and reliability of our chemical building blocks. Every drum is tested for identity, purity, and residual solvents before release. To maintain optimal stability, users should handle this material in a dry environment with minimal exposure to atmospheric moisture. Proper laboratory safety equipment, including gloves and eye protection, is recommended during weighing and transfer operations. Our packaging options are designed to protect the integrity of the product during international transit, ensuring it arrives in perfect condition for your synthesis protocols.

Storage and Stability

For long-term preservation of chemical integrity, store the container in a cool, dry place at temperatures below -20°C. Keep the vessel tightly closed when not in use to prevent hydration or degradation of the protecting groups. Under recommended storage conditions, Z-Arg(Pbf)-OH Cyclohexylamine Salt exhibits excellent stability over extended periods. Bulk quantities are available upon request, with flexible packaging solutions tailored to meet the specific volume requirements of large-scale manufacturing or laboratory research projects.