Peptides & Building Blocks

Z-L-Ala-L-Ala-OMe

  • CAS No.2483-51-4
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Z-L-Ala-L-Ala-OMe (CAS 2483-51-4) designed for efficient peptide synthesis. Available in bulk with full COA support.

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Product Technical Details

Product Overview

Z-L-Ala-L-Ala-OMe, also known as Z-L-Alanyl-L-Alanine Methyl Ester, is a highly refined protected dipeptide intermediate essential for advanced pharmaceutical synthesis. This compound features a benzyloxycarbonyl (Z or Cbz) protecting group on the N-terminus and a methyl ester on the C-terminus, making it an ideal building block for stepwise peptide assembly. Our manufacturing process ensures exceptional batch-to-batch consistency, meeting the rigorous demands of medicinal chemistry and process development teams worldwide.

As a key structural motif in peptide chemistry, this alanine derivative offers superior stability and reactivity profiles. It is extensively utilized in the construction of larger peptide chains where precise stereochemistry and protection group orthogonality are critical. We supply this material under strict quality control protocols, guaranteeing high optical purity and minimal impurities that could interfere with downstream coupling reactions.

Technical Specifications

ParameterSpecification
Chemical NameZ-L-Ala-L-Ala-OMe
CAS Number2483-51-4
Molecular FormulaC15H20N2O5
Molecular Weight308.33 g/mol
AppearanceWhite Powder
Melting Point93-94 °C
Purity (HPLC)≥98.0%
Storage Condition-15ºC, Sealed

Applications & Benefits

This protected dipeptide is primarily employed as a critical intermediate in the synthesis of complex therapeutic peptides and peptidomimetics. Its robust chemical structure allows for versatile manipulation during solid-phase or liquid-phase peptide synthesis. By utilizing our high-grade Z-L-Ala-L-Ala-OMe, research and production teams can minimize side reactions and improve overall yield in multi-step synthesis pathways.

  • High Optical Purity: Ensures correct stereochemistry in final peptide products.
  • Stable Protection: The Cbz group provides reliable N-terminal protection during various reaction conditions.
  • Versatile Reactivity: Suitable for diverse coupling strategies in pharmaceutical manufacturing.
  • Quality Assurance: Each batch is accompanied by a comprehensive Certificate of Analysis (COA).

Storage & Handling

To maintain optimal stability and potency, Z-L-Ala-L-Ala-OMe should be stored in a tightly closed container at temperatures below -15ºC. The material is hygroscopic and sensitive to prolonged exposure to ambient conditions. Therefore, it is recommended to keep the container in a cool, dry place away from direct light and moisture. When handling, appropriate personal protective equipment should be worn to prevent inhalation or skin contact. For large-scale industrial usage, we offer flexible packaging options including 25 kg drums or customized solutions based on specific logistical requirements.