Peptides & Building Blocks

Z-L-Tryptophan Methyl Ester

  • CAS No.2717-76-2
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

Premium grade Z-L-Tryptophan Methyl Ester (CAS 2717-76-2) designed for high-efficiency peptide synthesis and pharmaceutical intermediate applications with guaranteed purity.

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Product Technical Details

Product Overview

Z-L-Tryptophan Methyl Ester, commonly referenced in industry catalogs as Z-TRP-OME, represents a critical protected amino acid derivative utilized extensively in modern organic synthesis and peptide chemistry. This compound features a benzyloxycarbonyl (Cbz or Z) protecting group on the alpha-amino function and a methyl ester modification on the carboxyl terminus. Such structural configuration renders it an indispensable building block for the construction of complex peptide sequences and pharmaceutical active ingredients. Our manufacturing process ensures consistent quality and high chemical integrity, making it a reliable choice for research laboratories and industrial production facilities alike.

Technical Specifications

We adhere to strict quality control protocols to guarantee that every batch meets or exceeds industry standards for pharmaceutical intermediates. The physical and chemical properties are meticulously verified through advanced analytical instrumentation. Below is the detailed specification profile for this product.

ParameterSpecification
CAS Number2717-76-2
Molecular FormulaC20H20N2O4
Molecular Weight352.38 g/mol
AppearanceWhite Powders
Purity≥98.0%
Density1.269±0.06 g/cm3
Boiling Point579.3±50.0 °C (Predicted)
Flash Point417.1 °C

Industrial Applications

The primary utility of Z-L-Tryptophan Methyl Ester lies in its role as a versatile synthon for peptide bond formation. The indole side chain of the tryptophan residue requires careful handling during synthesis, and the Z-protection group offers robust stability against various reaction conditions while remaining removable under specific hydrogenolysis or acidic conditions. This balance makes it ideal for stepwise peptide assembly.

  • Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of peptide-based drugs and hormonal therapeutics.
  • Peptide Synthesis: Used in solid-phase and solution-phase peptide synthesis protocols requiring N-protected amino acid esters.
  • Organic Research: Employed in academic and industrial research for developing new synthetic methodologies involving tryptophan derivatives.
  • Chemical Biology: Utilized in the preparation of probes and labeled compounds for studying biological systems.

Quality Assurance and Storage

Quality is paramount in the supply of fine chemicals. Each production lot undergoes rigorous testing including HPLC, NMR, and melting point analysis to confirm identity and purity. A Certificate of Analysis (COA) is provided with every shipment to ensure full traceability and compliance with your internal quality standards. To maintain optimal stability, the product should be stored in a cool, dry environment away from direct sunlight and moisture. The container must remain tightly sealed when not in use to prevent hydrolysis of the methyl ester or degradation of the indole ring.

Packaging and Logistics

We understand the importance of secure packaging for international logistics. Standard packaging consists of 25 kg drums lined with high-quality polyethylene bags to ensure protection against contamination and humidity. Customized packaging solutions are available upon request to meet specific supply chain requirements. Our global distribution network ensures timely delivery to major chemical hubs worldwide, supported by comprehensive documentation for customs clearance and regulatory compliance.