Peptides & Building Blocks

Z-Val-Ala-OH

  • CAS No.24787-89-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Z-Val-Ala-OH peptide building block designed for professional pharmaceutical synthesis and research applications.

Request a Quote & Full COA

Product Technical Details

Product Overview

Z-Val-Ala-OH, chemically known as Carbobenzoxy-L-valyl-L-alanine, is a premium protected dipeptide building block extensively utilized in the pharmaceutical and biotechnology sectors. As a critical intermediate in peptide synthesis, this compound features a carbobenzoxy (Z or Cbz) protecting group on the N-terminus, ensuring stability during complex coupling reactions. Our manufacturing process adheres to strict quality control standards, delivering a product with exceptional purity suitable for demanding synthetic pathways.

The integration of Valine and Alanine residues makes this dipeptide a versatile fragment for constructing larger peptide chains. The Z-protection group offers orthogonal stability, allowing chemists to perform selective deprotection and coupling steps without compromising the integrity of the growing peptide sequence. This characteristic is vital for the efficient production of active pharmaceutical ingredients (APIs) and novel therapeutic candidates.

Technical Specifications

We maintain rigorous analytical standards to ensure consistency across all batches. Each lot undergoes comprehensive testing using high-performance liquid chromatography (HPLC) and nuclear magnetic resonance (NMR) spectroscopy. The following table outlines the key physical and chemical properties of our Z-Val-Ala-OH supply:

ParameterSpecification
CAS Number24787-89-1
Molecular FormulaC16H22N2O5
Molecular Weight322.36 g/mol
AppearanceWhite to Off-White Powder
Purity (HPLC)≥98.0%
Density1.13 g/cm3
Boiling Point513.5 °C at 760 mmHg
Flash Point264.4 °C

Industrial Applications

This protected dipeptide serves as a fundamental building block in the synthesis of various peptide-based drugs and research compounds. Its primary applications include:

  • Pharmaceutical Intermediate: Used in the multi-step synthesis of complex peptide APIs.
  • Medicinal Chemistry: Employed in structure-activity relationship (SAR) studies for drug discovery.
  • Biotechnology Research: Utilized as a standard reference or substrate in enzymatic assays.
  • Custom Peptide Synthesis: Integrated into longer sequences for specialized therapeutic developments.

Quality Assurance and Storage

Quality is paramount in chemical manufacturing. Our facility operates under Good Manufacturing Practice (GMP) guidelines to minimize impurities and ensure batch-to-batch reproducibility. A Certificate of Analysis (COA) is provided with every shipment, detailing test results against specified parameters.

To maintain optimal stability, Z-Val-Ala-OH should be stored in tightly closed containers in a cool, dry, and well-ventilated area. Protection from moisture and light is recommended to prevent degradation of the protecting group. Our standard packaging includes 25 kg drums, though we offer flexible customization to meet specific logistical requirements for global shipping.