Povidone K90: The Ultimate Pharmaceutical Excipient
Unlock superior drug formulations with the versatile binding, film-forming, and solubilizing properties of Povidone K90.
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Povidone K90
Povidone K90 is a high molecular weight, water-soluble polymer widely utilized in the pharmaceutical industry. Its exceptional properties as a binder, film-former, and solubilizer significantly enhance the quality and efficacy of various drug formulations, contributing to improved tablet integrity, drug solubility, and overall product stability.
- Leverage Povidone K90's properties as a highly adhesive polymer for superior tablet binding, ensuring robust tablet formation even at low concentrations, critical for effective pharmaceutical manufacturing.
- Enhance drug solubility and bioavailability by utilizing PVP K90's capabilities as a solubilizer, a key factor in developing effective oral solid dosage forms.
- Benefit from the water-soluble nature and excellent biocompatibility of PVP K90, making it a safe and versatile excipient for a broad spectrum of pharmaceutical applications.
- Utilize Povidone K90 for solid dispersion formulations to enhance the solubility of active pharmaceutical ingredients (APIs), a crucial step for poorly soluble drugs.
Key Advantages Offered
Superior Tablet Binding
Povidone K90 acts as an excellent tablet binder, enhancing the cohesiveness of powder mixtures during compression to produce tablets with optimal mechanical strength, a critical aspect of pharmaceutical quality control.
Enhanced Drug Solubilization
As a potent solubilizer, PVP K90 improves the dissolution rates of poorly water-soluble drugs, thereby increasing their bioavailability and therapeutic effectiveness.
Versatile Film-Forming Capabilities
The film-forming properties of Povidone K90 are essential for tablet coatings, providing a protective layer that can mask taste and odor, improve stability, and facilitate controlled drug release.
Key Applications
Tablet Manufacturing
Povidone K90 is extensively used as a binder in tablet formulations, ensuring the integrity and mechanical strength of tablets produced via wet granulation, dry granulation, or direct compression.
Coated Dosage Forms
Its film-forming ability makes PVP K90 ideal for coating tablets, offering protection, taste masking, and potential for controlled drug release mechanisms.
Oral Solid Dosage Forms
PVP K90 enhances the dissolution rates of poorly soluble drugs, significantly improving their bioavailability in oral solid dosage forms.
Cosmetic Formulations
In cosmetics, Povidone K90 serves as a film former, stabilizer, and viscosity modifier in hair care products, skin care lotions, and toothpaste.