2-Amino-5-Fluoropyridine: A Versatile Pharmaceutical Intermediate for Advanced Synthesis
Unlock innovation with our high-purity 2-Amino-5-Fluoropyridine, a key building block for your next breakthrough.
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2-Amino-5-Fluoropyridine
2-Amino-5-Fluoropyridine is a vital chemical compound with extensive applications in pharmaceuticals and agrochemicals. Its high purity, often exceeding 99%, makes it an indispensable building block for complex synthesis.
- The synthesis of 2-Amino-5-Fluoropyridine often starts from 2-aminopyridine and involves key steps like nitrification and the Schiemann reaction, crucial for introducing fluorine.
- This fluorinated pyridine derivative plays a critical role in creating biologically active heterocyclic compounds, essential for novel drug discovery.
- Its application as a pharmaceutical intermediate is significant for developing drugs like LBM415, a peptide deformylase inhibitor.
- In agrochemicals, it serves as a building block for effective herbicides and fungicides, enhancing crop protection.
Advantages Provided by the Product
Enhanced Biological Activity
The incorporation of fluorine through 2-Amino-5-Fluoropyridine can significantly improve the pharmacokinetic properties of resulting pharmaceuticals, leading to better efficacy.
Versatile Synthesis Intermediate
Its reactivity allows for diverse chemical transformations, making it a versatile component in the synthesis of a wide range of complex organic molecules.
Application in Radiochemistry
The compound's potential in radiochemistry, particularly for PET imaging when labeled with fluorine-18, opens avenues for advanced medical diagnostics and research.
Key Applications
Pharmaceutical Synthesis
As a key pharmaceutical intermediate, 2-Amino-5-Fluoropyridine is vital for the development of new therapeutic agents, aiding in the synthesis of drugs for various conditions.
Agrochemical Development
In the agrochemical sector, it is utilized for synthesizing advanced herbicides and fungicides, contributing to sustainable agriculture and crop yield improvement.
Medicinal Chemistry
Its role in creating novel anticancer agents and other biologically active compounds underscores its importance in advancing medicinal chemistry research.
Radiopharmaceutical Research
The ability to be labeled with isotopes like Fluorine-18 makes it valuable for PET imaging, assisting in disease diagnosis and understanding metabolic processes.