2-Bromoethyl Benzene: A Crucial Intermediate in Pharmaceutical Synthesis and Organic Chemistry
Discover the chemical properties and diverse applications of 2-Bromoethyl Benzene (CAS 103-63-9), a vital building block for advanced organic synthesis and pharmaceutical development. Explore its role in creating effective antimicrobial agents and its utility across various chemical industries.
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(2-Bromoethyl)benzene
We are a reliable supplier in China of (2-Bromoethyl)benzene (CAS 103-63-9), a crucial aryl bromide compound. Its unique structure and chemical properties make it an indispensable asset in organic chemistry, serving as a building block for complex organic molecules. In pharmaceutical synthesis, it plays a key role in creating potent antimicrobial agents with high enzymic stability and low toxicity, demonstrating its significant value in drug development.
- Introduction to 2-Bromoethyl Benzene Synthesis: This section delves into the primary method of synthesizing (2-Bromoethyl)benzene, which involves the anti-Markovnikov addition of hydrogen bromide to styrene, often using catalysts like azobisisobutyronitrile. Achieving a high yield of 95% is possible through optimized reaction conditions, making it an efficient process.
- Pharmaceutical Intermediate Applications: (2-Bromoethyl)benzene is a key reactant in the synthesis of various pharmaceutical compounds, notably antimicrobial β-peptidomimetics. These synthesized molecules exhibit significant antimicrobial activity against a range of bacteria, including MRSA and E. coli, showcasing their potential as advanced therapeutic agents.
- Broader Organic Synthesis Utility: Beyond pharmaceuticals, (2-Bromoethyl)benzene is widely used in organic synthesis for creating diverse chemical structures. Its balanced reactivity and stability make it a versatile intermediate for industrial processes and cutting-edge research.
- Chemical Properties and Stability: Possessing a melting point of -56 °C and a boiling point of 220-221 °C, (2-Bromoethyl)benzene is a stable compound. It is incompatible with strong oxidizing agents, requiring careful handling and storage conditions, typically between 2-8°C.
Advantages Provided by the Product
Versatile Building Block
As a key building block for complex organic molecules, (2-Bromoethyl)benzene facilitates the creation of diverse chemical structures, supporting advanced organic synthesis.
Pharmaceutical Synthesis Excellence
Its application in synthesizing antimicrobial β-peptidomimetics highlights its critical role in developing more stable and less toxic drug candidates, contributing to pharmaceutical research and development.
Industrial Applicability
From flame retardants to fragrance intermediates, (2-Bromoethyl)benzene offers broad utility across various industries, underscoring its importance in different manufacturing processes.
Key Applications
Pharmaceutical Intermediates
Utilized in the synthesis of active pharmaceutical ingredients (APIs), especially in developing novel antimicrobial agents and drug candidates.
Organic Synthesis
Serves as a fundamental intermediate for a wide array of organic reactions, enabling the construction of intricate molecular architectures.
Fragrance Industry
Acts as a precursor in the creation of unique scents and fragrances, contributing to the consumer product sector.
Flame Retardants
Finds application in material science as a component in flame retardant formulations, enhancing safety standards.