Exploring 2-Fluoro-3-Trifluoromethylpyridine: Properties and Applications
A critical building block for pharmaceutical and agrochemical innovation, offering enhanced synthesis capabilities.
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2-Fluoro-3-trifluoromethylpyridine
2-Fluoro-3-trifluoromethylpyridine, identified by its CAS number 65753-52-8, is a specialized chemical compound vital for organic synthesis. It is a colorless transparent liquid that stands out due to its unique physical and chemical properties, making it an essential intermediate in various synthetic processes.
- High Purity Synthesis Intermediate: This compound serves as a crucial building block for developing innovative products in pharmaceuticals and agrochemicals, ensuring exceptional quality with an assay of at least 98.0%.
- Key Pharmaceutical Intermediate: It is used as a synthetic intermediate for the development of antihypertensive β-adrenergic blocking agents and HCV NS5B thumb pocket 2 allosteric inhibitors, vital for cardiovascular and Hepatitis C treatments.
- Versatile Agrochemical Precursor: The compound finds use in agrochemical development, where trifluoromethylpyridine derivatives are integral to creating effective pesticides and herbicides, enhancing lipophilicity and environmental persistence.
- Fluorinated Pyridine Chemistry: Its structure, featuring fluorine atoms on the pyridine ring, enhances electrophilic nature and metabolic stability, making it valuable in creating compounds with improved biological properties.
Key Advantages
Enhanced Reactivity
The strategically positioned fluorine atoms on the pyridine ring of 2-Fluoro-3-trifluoromethylpyridine enhance its electrophilic nature, facilitating unique reaction pathways for complex chemical syntheses.
Improved Biological Properties
Fluorine incorporation, particularly the trifluoromethyl group, often leads to enhanced metabolic stability and bioavailability in downstream pharmaceutical applications, as well as improved efficacy in agrochemicals.
Broad Application Scope
This compound is a versatile intermediate, supporting the synthesis of a wide array of bioactive molecules, from life-saving drugs to essential crop protection agents, demonstrating its value in modern chemical R&D.
Key Applications
Pharmaceutical Synthesis
Utilized in the creation of antihypertensive agents and antiviral drugs, leveraging its unique structure for improved therapeutic outcomes.
Agrochemical Development
Serves as a critical building block for novel pesticides and herbicides, enhancing crop protection and yield through its fluorinated pyridine structure.
Organic Synthesis Intermediate
Acts as a fundamental component in complex organic syntheses, enabling the creation of advanced materials and specialized chemical compounds.
Research & Development
Essential for researchers exploring new chemical entities and functional materials, providing a reliable starting point for innovative discoveries.