2,4,5-Trifluorophenylacetic Acid: A Key Intermediate for Pharmaceuticals and Advanced Materials
Discover the critical role of 2,4,5-Trifluorophenylacetic Acid in advancing pharmaceutical and chemical innovations.
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2,4,5-Trifluorophenylacetic Acid
As a pivotal chemical compound, 2,4,5-Trifluorophenylacetic Acid (CAS: 209995-38-0) serves as an indispensable intermediate in the synthesis of numerous pharmacologically active compounds and advanced materials. Its unique fluorinated structure makes it highly sought after in cutting-edge chemical research and industrial applications.
- The synthesis of Sitagliptin, a vital DPP-4 inhibitor for type-2 diabetes management, relies heavily on 2,4,5-trifluorophenylacetic acid as a critical intermediate.
- This compound is instrumental in the development of EGFR/ErbB-2-kinase inhibitors, expanding its utility in targeted cancer therapies.
- Its application extends to the synthesis of novel imidazopyrazinone derivatives, showcasing its potential in new therapeutic avenues.
- The chemical synthesis of 2,4,5-Trifluorophenylacetic Acid is optimized for high purity and yield, ensuring reliable performance in downstream applications.
Advantages of Using 2,4,5-Trifluorophenylacetic Acid
Enhanced Bioactivity
The strategic placement of fluorine atoms in the 2,4,5-trifluorophenylacetic acid molecule significantly enhances the bioactivity and chemical stability of the resulting pharmaceutical compounds, a key factor in developing potent drug candidates.
Versatile Intermediate
As a versatile building block, 2,4,5-trifluorophenylacetic acid is crucial for a wide range of organic synthesis projects, from pharmaceutical intermediates to specialty chemicals, providing flexibility for researchers and manufacturers.
Quality Assurance
Suppliers like Ningbo Inno Pharmchem ensure the highest standards of quality and purity for 2,4,5-trifluorophenylacetic acid, meeting the stringent requirements of the pharmaceutical industry and ensuring consistent results in complex syntheses.
Key Applications
Pharmaceutical Development
Crucial for the synthesis of active pharmaceutical ingredients (APIs), particularly those targeting metabolic disorders and cancers, leveraging the unique properties of 2,4,5-trifluorophenylacetic acid in drug design.
Advanced Chemical Synthesis
Utilized as a building block in complex organic synthesis, enabling the creation of novel fluorinated compounds with tailored properties for diverse industrial applications.
Type-2 Diabetes Treatment
Plays a vital role in the production pathway of Sitagliptin, a key dipeptidyl peptidase-4 (DPP-4) inhibitor, contributing to effective diabetes management.
Kinase Inhibitor Synthesis
Essential for developing EGFR/ErbB-2-kinase inhibitors, which are critical in targeted therapies for various forms of cancer.