5-Chloro-2,3-diphenylpyrazine: A Key Intermediate in Pharmaceutical Synthesis and Organic Chemistry
Unlock advanced organic synthesis with this vital diphenylpyrazine building block for pharmaceutical innovation.
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5-Chloro-2,3-diphenylpyrazine
This compound, identified by CAS 41270-66-0, is a crucial chemical intermediate, particularly recognized for its role in the synthesis of Selexipag, a medication used to treat pulmonary arterial hypertension. Its structural features, including the reactive chlorine atom and the diphenylpyrazine core, make it highly valuable for a wide range of organic synthesis applications, including nucleophilic aromatic substitution and palladium-catalyzed cross-coupling reactions.
- Leverage the significance of 5-chloro-2,3-diphenylpyrazine synthesis for advanced organic transformations. This compound is pivotal for creating complex molecular structures.
- Explore the utility of the CAS 41270-66-0 number in sourcing this essential pharmaceutical intermediate. Accurate identification is key for procurement and research.
- Integrate this compound into your Selexipag intermediate synthesis workflow for reliable drug development. Its precise structure facilitates efficient downstream reactions.
- Discover the power of palladium catalyzed cross-coupling reactions using this versatile diphenylpyrazine derivative. It enables the formation of new carbon-carbon bonds with high efficiency.
Key Advantages and Properties
Versatile Reactivity
The presence of a reactive chlorine atom allows for facile nucleophilic aromatic substitution and participation in various palladium-catalyzed cross-coupling reactions, enabling diverse functionalization for your synthetic needs.
Pharmaceutical Intermediate
As a key building block for Selexipag, this compound is indispensable for pharmaceutical research and development targeting conditions like pulmonary arterial hypertension, contributing to the advancement of medical treatments.
Reliable Synthesis & Purity
Utilize optimized synthetic routes that ensure high purity and yield, crucial for downstream applications in drug synthesis and fine chemical manufacturing, ensuring consistent results.
Key Applications
Pharmaceutical Synthesis
Essential intermediate for the synthesis of Selexipag, a crucial drug for treating pulmonary arterial hypertension, demonstrating its importance in the pharmaceutical industry.
Organic Synthesis
Serves as a versatile building block for creating complex organic molecules through reactions like nucleophilic aromatic substitution and various cross-coupling methods.
Materials Science
Potential use in coordination chemistry as a ligand for transition metals, contributing to the development of advanced materials with specific electronic or optical properties.
Research and Development
A valuable compound for academic and industrial research, enabling the exploration of new synthetic methodologies and the discovery of novel biologically active compounds.