Discover EPZ-5676 (Pinometostat): A Potent DOT1L Inhibitor for Leukemia Research
As a leading manufacturer and supplier in China, we offer EPZ-5676, also known as Pinometostat, a highly selective DOT1L inhibitor crucial for MLL-rearranged leukemia research and pharmaceutical development. Learn about its mechanism and procurement options.
Get a Quote & SampleUnlocking Therapeutic Potential with EPZ-5676
EPZ-5676 (Pinometostat)
We provide high-purity EPZ-5676 (Pinometostat), a critical S-adenosyl methionine (SAM) competitive inhibitor of DOT1L. As a trusted supplier, our commitment is to deliver exceptional quality for your pharmaceutical R&D needs. Explore why purchasing from a reputable manufacturer in China ensures reliability and cost-effectiveness for your drug discovery programs.
- Potent DOT1L Inhibition: Our EPZ-5676 offers potent and selective inhibition of DOT1L, a key enzyme in MLL-fusion leukemia. This makes it an indispensable tool for researchers in this field.
- Mechanism of Action: Understand how Pinometostat works by occupying the SAM binding pocket of DOT1L, leading to conformational changes and effective blockage of H3K79 methylation.
- Research & Clinical Applications: EPZ-5676 has demonstrated efficacy in preclinical models and is progressing through clinical trials, highlighting its significance in developing novel cancer therapies.
- Quality Assurance: Rely on our stringent quality control processes to ensure the purity and consistency of EPZ-5676, essential for reproducible research results. We are a trusted manufacturer and supplier.
Advantages of Sourcing EPZ-5676 from Us
High Purity & Selectivity
Our EPZ-5676 is characterized by high purity (≥95% by HPLC) and excellent selectivity against other methyltransferases, ensuring precise and reliable experimental outcomes for your leukemia treatment research.
Reliable Supply Chain
As a dedicated manufacturer and supplier in China, we ensure a stable and dependable supply of EPZ-5676. For bulk purchases or custom quotes, contact us to secure your supply chain for this vital pharmaceutical intermediate.
Expert Technical Support
Leverage our expertise. We provide comprehensive support to help you understand the specifications, solubility, and handling of EPZ-5676, facilitating its effective use in your research and development projects.
Key Applications of EPZ-5676 (Pinometostat)
Oncology Drug Development
EPZ-5676 is a critical component in the development of new cancer therapies, particularly for hematologic malignancies like MLL-rearranged leukemia. Explore its potential in your drug discovery pipeline.
Leukemia Research
Investigate the therapeutic mechanisms and efficacy of DOT1L inhibition in leukemia models. Our high-quality EPZ-5676 is essential for accurate and reproducible research findings.
Epigenetic Therapy Studies
Delve into the role of H3K79 methylation in cancer. EPZ-5676 serves as a vital tool for studying epigenetic modifications and their impact on cellular function and disease progression.
Pharmaceutical Intermediate Sourcing
Source this crucial pharmaceutical intermediate from a reliable manufacturer. We cater to research institutions and pharmaceutical companies seeking bulk quantities and competitive pricing.