Fmoc-D-4-Chlorophenylalanine: A Key Building Block for Advanced Peptide Synthesis

Unlock the power of complex peptide structures with Fmoc-D-4-Chlorophenylalanine, a premium amino acid derivative essential for cutting-edge peptide synthesis and drug discovery. Explore its role in creating novel therapeutics and advancing life science research.

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Advantages of Using This Product

Milder Synthesis Conditions

Fmoc chemistry, utilizing building blocks like Fmoc-D-4-Chlorophenylalanine, offers milder deprotection and coupling steps compared to traditional methods, reducing the risk of peptide degradation and epimerization, which is crucial for maintaining the integrity of complex sequences.

True Orthogonality

The Fmoc group is stable under acidic conditions but easily cleaved by a base, providing true orthogonality with acid-labile side-chain protecting groups. This compatibility enhances the efficiency and success rate in peptide synthesis, a key aspect when producing pharmaceutical intermediates.

Facilitates Complex Peptides

As a specialized amino acid derivative, Fmoc-D-4-Chlorophenylalanine enables the synthesis of peptides with modified side chains, crucial for creating targeted therapeutics. This capability is vital for advancing drug development goals.

Key Applications

Peptide Synthesis

A fundamental building block in both research and industrial settings for Fmoc solid-phase peptide synthesis (SPPS), enabling the construction of diverse peptide sequences.

Drug Development

Essential for synthesizing novel peptide-based drugs and therapeutic agents, contributing to pharmaceutical innovation and the creation of specific drug development intermediates.

Bioconjugation

Used in linking peptides to other molecules, enhancing drug delivery, imaging agents, or diagnostic tools, supporting advanced bioconjugation techniques.

Protein Engineering

Aids in modifying protein structures or creating peptidomimetics to improve stability, activity, or function, supporting research in protein engineering.