Folinic Acid CAS 58-05-9: A Comprehensive Guide to its Properties, Applications, and Benefits
Discover the critical role of Folinic Acid (Leucovorin) in modern medicine and research. Learn about its chemical properties, key applications, and why it's a vital compound for various therapeutic and scientific endeavors.
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Folinic Acid
As a leading supplier in China, NINGBO INNO PHARMCHEM CO.,LTD. offers high-quality Folinic Acid (CAS 58-05-9). This metabolically active form of folate plays a crucial role in cellular metabolism and is extensively used as an adjuvant in chemotherapy. Its ability to bypass the dihydrofolate reductase (DHFR) inhibition makes it invaluable in mitigating the toxic effects of drugs like methotrexate, thereby supporting folate-dependent processes. Folinic acid also enhances the efficacy of 5-fluorouracil in cancer treatment. We ensure adherence to USP, BP, EP, and FCC standards, providing reliability for your research and pharmaceutical needs.
- Folinic Acid Chemical Properties: We provide detailed insights into the chemical characteristics of Folinic Acid, ensuring you have the necessary data for your applications.
- Leucovorin Medical Applications: Explore the diverse medical uses of Leucovorin, particularly its role as a critical rescue agent in cancer therapy.
- Folinic Acid Supplier China: Trust NINGBO INNO PHARMCHEM CO.,LTD. as your reliable source for high-purity Folinic Acid, ensuring consistent quality and supply chain stability.
- Folate Metabolism Research: Our product is essential for researchers investigating folate metabolism pathways and their impact on various biological processes.
Key Advantages Offered
Enhanced Therapeutic Efficacy
Leverage the synergistic effects of Folinic Acid when combined with chemotherapy agents like 5-fluorouracil, maximizing treatment outcomes in colorectal cancer and other regimens. This makes it a key compound for Buy Folinic acid 58-05-9.
Reduced Chemotherapy Toxicity
Folinic Acid acts as a vital rescue agent, significantly decreasing the severe side effects associated with methotrexate treatment, thereby improving patient tolerance and quality of life. This is a crucial aspect of Methotrexate rescue agent applications.
Support for Genetic Variations
For individuals with MTHFR mutations, Folinic Acid offers a more readily usable form of folate, supporting critical metabolic pathways even when folic acid conversion is impaired. This addresses the need for MTHFR mutation support.
Key Applications
Oncology Support
Essential in combination therapies, Folinic Acid enhances the effectiveness of chemotherapy drugs like 5-fluorouracil and reduces the toxicity of methotrexate, contributing to better patient outcomes in cancer treatment.
Biochemical Research
Used as a cofactor in various enzymatic reactions and as a reference compound in analytical chemistry, aiding in the quantification of folate levels and the development of new diagnostic assays.
Nutritional Science
Valuable for studies focusing on folate absorption, metabolism, and the impact of genetic factors like MTHFR mutations on nutrient utilization, supporting research in Nutritional Biochemistry.
Pharmaceutical Development
Serves as a critical intermediate in the synthesis of various pharmaceutical compounds and as a key component in drug formulations, highlighting its importance for Pharmaceutical Intermediate Sourcing.