Hexamethyldisilazane (HMDS): Your Premier Silylating Agent Supplier
Discover the exceptional versatility of Hexamethyldisilazane (HMDS), a critical silylating agent for advanced chemical synthesis. As a trusted manufacturer and supplier in China, we provide high-purity HMDS essential for pharmaceutical intermediates and semiconductor applications, ensuring optimal performance and reliability for your critical processes. Get a quote today!
Get a Quote & SampleUnlocking Chemical Potential with High-Purity HMDS

Hexamethyldisilazane (HMDS) - CAS 999-97-3
As a leading manufacturer and supplier of specialty chemicals, we offer Hexamethyldisilazane (HMDS) with a minimum purity of 99%. HMDS serves as a powerful silylating agent, indispensable for introducing the trimethylsilyl group. This capability is vital for protecting reactive functional groups in organic synthesis, enhancing product stability, and enabling complex chemical transformations. Our commitment as a reliable HMDS supplier ensures consistent quality and competitive pricing for your manufacturing needs.
- Silylating Agent Excellence: Leverage HMDS for superior protection of hydroxylic groups and other reactive functionalities in your pharmaceutical synthesis projects.
- Semiconductor Adhesion: Utilize HMDS as an effective adhesion promoter for photoresists in microelectronic fabrication, ensuring precise pattern transfer.
- Pharmaceutical Intermediate Role: Source high-purity HMDS from a trusted manufacturer for the synthesis of critical drug intermediates and derivatives.
- Surface Modification Benefits: Employ HMDS for surface treatment of materials like silica and titanium powders, improving their dispersibility and properties.
Key Advantages of Sourcing Our HMDS
Enhanced Chemical Stability
Our HMDS enables the formation of silylated derivatives that exhibit significantly improved chemical stability compared to the parent compounds, facilitating challenging synthetic routes.
No HCl Acceptor Required
A major advantage of HMDS over chlorosilanes is that it does not require a base as a hydrochloric acid acceptor, simplifying reaction procedures and reducing by-products.
Versatile Application Spectrum
From pharmaceuticals to electronics, HMDS offers broad utility as a derivatization agent for analytical investigations and as a key intermediate in numerous industrial processes.
Diverse Applications of Hexamethyldisilazane
Pharmaceutical Synthesis
HMDS is crucial for protecting functional groups in antibiotics, aiding in the production of valuable pharmaceutical intermediates and derivatives. Purchase HMDS for your API synthesis.
Semiconductor Industry
Its role as an adhesion promoter for photoresists in the semiconductor industry makes HMDS a vital component for microelectronic manufacturing. Inquire about bulk HMDS supply.
Surface Modification
HMDS is used to hydrophobize surfaces of fillers like diatomite and titanium powder, enhancing their compatibility and performance in various composite materials.
Analytical Chemistry
In GC-MS analysis, HMDS is used to derivatize volatile compounds, improving their detection limits and chromatographic behavior. Buy HMDS for your analytical needs.