Highly Enantioselective Synthesis of (R)-1,3-Butanediol via Biocatalytic Deracemization
Discover the advanced biocatalytic cascade deracemization method for producing high-purity (R)-1,3-Butanediol, an essential chiral intermediate for pharmaceutical and fragrance industries. Learn how optimized microbial processes offer superior yields and enantiomeric excess.
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(R)-1,3-Butanediol (CAS 6290-03-5)
As a leading manufacturer and supplier of fine chemicals in China, we present a breakthrough in chiral synthesis. Our optimized biocatalytic process efficiently converts racemic 1,3-butanediol into the highly pure (R)-enantiomer, offering significant advantages for your R&D and production needs. We ensure stable supply and competitive price for this critical building block.
- Efficient Stereoinverting Cascade: Utilize a novel oxidation-reduction cascade system for maximizing the yield of (R)-1,3-Butanediol from racemic mixtures.
- Exceptional Enantiomeric Purity: Achieve over 99% enantiomeric excess (ee), crucial for demanding pharmaceutical and specialty chemical applications.
- Cost-Effective Production: Source your (R)-1,3-Butanediol with a competitive price, making advanced chiral synthesis accessible for large-scale industrial use.
- Sustainable Manufacturing: Benefit from a green chemistry approach that minimizes substrate waste and employs mild reaction conditions, aligning with environmental best practices.
Key Advantages of Our (R)-1,3-Butanediol Process
Superior Enantioselectivity
Our carefully screened microbial strains, including C. parapsilosis QC-76 and P. kudriavzevii QC-1, guarantee precise stereoselective oxidation and reduction, leading to a final product with over 99% ee. This is essential when you need to buy intermediates for chiral drugs.
High Yield from Racemate
This deracemization process overcomes the theoretical 50% yield limitation of kinetic resolution, transforming racemic 1,3-butanediol into the desired (R)-enantiomer with significantly reduced material waste. Find a reliable supplier for this advanced synthesis route.
Streamlined Production
The step-by-step cascade approach, avoiding intermediate isolation, simplifies operational procedures and enhances overall process efficiency. Explore options to purchase this high-value chemical from a trusted manufacturer.
Diverse Applications of (R)-1,3-Butanediol
Pharmaceutical Intermediates
Critical for the synthesis of β-lactam antibiotics, azetidinone derivatives, and other chiral pharmaceuticals. Ensure your supply chain by contacting our sales team for a quote.
Fragrances and Flavors
Used as a building block in the creation of complex aroma compounds and flavor profiles, adding value to consumer products.
Pheromones and Insecticides
Essential component in the synthesis of specific pheromones for pest control and various insecticide formulations.
Specialty Chemicals
Its unique chiral structure makes it valuable in the synthesis of other advanced fine chemicals and performance materials.