High-Purity Peptide Linker: MC-Val-Cit-PAB-OH Supplier for Antibody-Drug Conjugates (ADCs)
Discover the advanced MC-Val-Cit-PAB-OH linker, a critical component for developing cutting-edge Antibody-Drug Conjugates (ADCs). As a leading manufacturer and supplier, we provide high-purity peptide linkers designed for precise drug delivery and enhanced therapeutic efficacy. Explore our competitive prices and reliable sourcing from China.
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MC-Val-Cit-PAB-OH: The Precision Linker
As a premier NINGBO INNO PHARMCHEM CO.,LTD. manufacturer and supplier, we offer MC-Val-Cit-PAB-OH (CAS 159857-80-4), a high-purity peptide linker essential for the development of Antibody-Drug Conjugates (ADCs). Our commitment to quality ensures that you receive a product designed for optimal performance in targeted therapeutics and diagnostic probes. We are your trusted source for competitive pricing and reliable supply.
- Precisely Engineered for ADCs: This linker features a maleimidocaproyl (MC) group for selective thiol conjugation, ensuring stable attachment to antibodies.
- Enzymatically Cleavable Design: The Val-Cit dipeptide sequence is specifically designed for cleavage by Cathepsin B, facilitating targeted payload release within cancer cells.
- Efficient Payload Release: The para-aminobenzyl (PAB) self-immolative spacer ensures rapid and complete drug release after enzymatic cleavage, maximizing therapeutic impact.
- Global Sourcing Advantage: Partner with a leading manufacturer and supplier in China for consistent quality, competitive prices, and a stable supply chain for your research and development needs.
Key Advantages of Our Peptide Linkers
Enhanced Stability and Specificity
Our MC-Val-Cit-PAB-OH linker offers superior stability in systemic circulation, minimizing off-target effects and ensuring that the cytotoxic payload is released specifically within tumor cells. This specificity is crucial for improving treatment outcomes and reducing patient side effects. As your dedicated supplier, we guarantee this level of precision.
Optimized for Bioconjugation
The MC group's reactivity with thiols, combined with the cleavable Val-Cit sequence, makes this linker exceptionally versatile for various bioconjugation strategies. Researchers and formulators can rely on this product for reproducible results in developing novel targeted therapeutics. Inquire about bulk purchase options for your manufacturing needs.
Cost-Effective Manufacturing and Supply
As a reputable NINGBO INNO PHARMCHEM CO.,LTD. manufacturer, we leverage efficient production processes to offer MC-Val-Cit-PAB-OH at competitive prices. We are committed to being your reliable supplier, ensuring you can procure high-quality ADC linkers without compromising your budget. Contact us for a quote and sample.
Diverse Applications in Advanced Therapeutics
Antibody-Drug Conjugates (ADCs)
The primary application of MC-Val-Cit-PAB-OH is in the construction of ADCs, linking potent cytotoxic drugs to antibodies that target cancer cells. This provides a highly specific and effective approach to cancer therapy, ensuring drug delivery directly to tumor sites. As your trusted manufacturer, we support your ADC development.
Targeted Therapeutics
Beyond ADCs, this linker is instrumental in developing other targeted therapeutic agents, enabling precise delivery of active compounds to specific cellular targets. Researchers seeking specialized pharmaceutical intermediates can find a reliable supplier in us.
Diagnostic Probe Development
MC-Val-Cit-PAB-OH can be incorporated into diagnostic probes, allowing for the controlled release of imaging agents or markers at specific disease sites, improving diagnostic accuracy and early detection. We are your go-to source for these advanced chemical solutions.
Prodrug Strategies
The cleavable nature of this linker makes it ideal for prodrug development, where the active drug is released only upon encountering specific biological triggers, such as enzymes overexpressed in disease environments. Explore our comprehensive offerings as a leading China-based manufacturer.