Microcrystalline Cellulose pH102: The Essential Pharmaceutical Excipient
Unlock superior tablet and capsule formulations with the unparalleled performance of Microcrystalline Cellulose pH102.
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Microcrystalline Cellulose pH102
Microcrystalline Cellulose pH102 is a highly refined and purified form of cellulose, derived from plant fiber. Its key value lies in its exceptional performance as a pharmaceutical excipient, particularly for direct compression tablet manufacturing and capsule filling. It serves as a versatile diluent, binder, and disintegrant, contributing to tablet hardness, uniformity, and efficient drug release.
- As a tablet and capsule diluent, microcrystalline cellulose pH102 provides essential bulk for low-dose active ingredients, ensuring accurate dosing and consistent tablet weight.
- Leverage MCC for direct compression, benefiting from its high compressibility and plastic deformation properties that create strong tablet bonds with minimal compression force.
- Experience improved tabletability with microcrystalline cellulose pH102, as its particle size and moisture content are optimized for robust tablet formation and reduced friability.
- Utilize MCC as a binder and disintegrant, facilitating tablet cohesion while ensuring prompt tablet breakdown for optimal drug release and bioavailability.
Key Advantages
Exceptional Compressibility
Microcrystalline cellulose pH102 is renowned for its superior compressibility, enabling the creation of tablets with excellent hardness and low friability, even under low compression forces. This property is crucial for direct compression tablet manufacturing.
Enhanced Flow Properties
The optimized particle size distribution of MCC pH102 contributes to improved powder flow, which is essential for consistent die filling in tablet presses and capsule filling machines, minimizing manufacturing issues and ensuring product uniformity.
Versatile Functionality
MCC pH102 acts as a multifunctional excipient, serving as a binder, diluent, disintegrant, and even a lubricant. This versatility simplifies formulations and can reduce the number of excipients required.
Key Applications
Tablet Manufacturing
As a primary diluent and binder, MCC pH102 is vital for producing high-quality tablets via direct compression or wet granulation, ensuring optimal hardness and disintegration.
Capsule Filling
The excellent flowability and compressibility of MCC pH102 make it an ideal filler for capsule formulations, ensuring accurate fill weights and consistent product uniformity.
Wet Granulation
MCC pH102's wicking action facilitates rapid wetting and uniform granulation, improving the overall process efficiency and the quality of the wet mass.
Nutraceutical Formulations
Beyond pharmaceuticals, MCC pH102 is widely used in nutraceuticals as a binder and bulking agent, enhancing the stability and manufacturability of dietary supplements.