N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide Hydrochloride: Your Key to Advanced Peptide Synthesis & Bioconjugation
Discover the power of EDC HCl, a crucial water-soluble carbodiimide for efficient amide bond formation, peptide synthesis, and versatile bioconjugation. Unlock new possibilities in your research and development.
Get a Quote & SampleThe Core Value of EDC HCl
N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride
As a leading supplier in China, we offer high-quality N-(3-Dimethylaminopropyl)-N'-ethylcarbodiimide hydrochloride (EDC HCl), a water-soluble carbodiimide essential for various chemical transformations. Its ability to activate carboxyl groups makes it invaluable for forming amide bonds, a cornerstone of peptide synthesis. Moreover, its utility extends to bioconjugation, enabling the linking of diverse molecules for advanced research and applications.
- Facilitates efficient peptide synthesis by acting as a crucial coupling agent for amide bond formation, a key process in creating complex peptides and proteins.
- Enables versatile bioconjugation reactions, allowing the covalent linkage of biomolecules such as proteins, nucleic acids, and haptens for applications in diagnostics and therapeutics.
- Offers easy byproduct removal, as the urea byproduct formed during coupling is water-soluble, simplifying purification processes compared to other carbodiimides.
- Acts as a reliable activating agent for carboxyl groups, making it a preferred choice for researchers and manufacturers in pharmaceutical and life science industries.
Key Advantages of Using EDC HCl
Superior Water Solubility
EDC HCl's excellent solubility in water and organic solvents simplifies reaction setup and workup, making it a preferred choice for many peptide synthesis protocols.
Enhanced Coupling Efficiency
When used with additives like NHS, EDC HCl significantly boosts coupling efficiency in bioconjugation reactions, ensuring higher yields and purer products.
Simplified Purification
The water-soluble nature of the byproduct urea allows for easy removal through aqueous washes, streamlining the purification process after amide bond formation.
Key Applications
Peptide Synthesis
EDC HCl is fundamental for activating carboxyl groups, enabling the sequential addition of amino acids to form peptide bonds, crucial for synthesizing peptides and proteins.
Biomolecule Immobilization
It is instrumental in immobilizing biomolecules onto solid supports for biosensors, affinity chromatography, and diagnostic assays.
Conjugation Reactions
EDC HCl facilitates the linking of haptens to carrier proteins for vaccine development and the creation of antibody-drug conjugates.
General Amide & Ester Formation
Beyond specialized applications, EDC HCl serves as a general reagent for forming amide and ester bonds in various organic synthesis pathways.