N-epsilon-Benzyloxycarbonyl-D-lysine: Synthesis, Applications, and Quality Control for Peptide Research
A key protected amino acid essential for advanced peptide synthesis and biochemical research.
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N-epsilon-Benzyloxycarbonyl-D-lysine
N-epsilon-Benzyloxycarbonyl-D-lysine, identified by CAS 34404-32-5, is a vital protected amino acid utilized extensively in sophisticated peptide synthesis workflows. Its molecular formula C14H20N2O4 and molecular weight of 280.32 underscore its specific chemical nature.
- This compound is instrumental in achieving orthogonal protection strategies, a critical aspect for building complex peptide sequences with precision.
- Researchers leverage H-D-Lys(Z)-OH to optimize synthesis methodologies, aiming for higher yields and purity of target peptides.
- Its utility extends to probing protein structure and function by allowing the controlled incorporation of modified residues into peptide chains.
- Understanding the synthesis and applications of H-D-Lys(Z)-OH is key for advancing biochemical research and development.
Advantages Provided by the Product
Enhanced Peptide Purity
Utilizing protected amino acids like N-epsilon-Benzyloxycarbonyl-D-lysine helps minimize side reactions during peptide synthesis, leading to higher purity of the final peptide product.
Facilitates Complex Peptide Structures
The strategic use of protecting groups, such as the benzyloxycarbonyl (Z) group in H-D-Lys(Z)-OH, allows for selective deprotection steps, enabling the construction of intricate and functional peptide architectures.
Enables Structure-Function Studies
Researchers can incorporate modified amino acids, like this D-lysine derivative, into peptides to investigate how specific structural modifications influence biological activity and protein-protein interactions.
Key Applications
Peptide Synthesis
N-epsilon-Benzyloxycarbonyl-D-lysine is a fundamental building block in solid-phase and solution-phase peptide synthesis, ensuring the integrity of lysine side chains.
Biochemical Research
Its application extends to various biochemical research areas, particularly in studies focusing on enzyme kinetics, receptor binding, and signaling pathways.
Drug Discovery
As a versatile intermediate, it plays a role in the development of novel peptide-based therapeutics and diagnostic agents.
Protein Structure Elucidation
Incorporating this modified amino acid aids in understanding how subtle structural changes impact protein folding, stability, and overall function.