Nitroxoline CAS 4008-48-4: A Comprehensive Guide to Its Properties, Applications, and Benefits

Discover the multifaceted potential of Nitroxoline (CAS 4008-48-4), a compound with a rich history and exciting future in antibacterial therapies, cancer research, and beyond. Explore its chemical intricacies and diverse applications.

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Advantages Offered by Nitroxoline

Broad Spectrum Activity

Nitroxoline demonstrates significant antibacterial efficacy against a wide range of Gram-negative bacteria, offering a potential solution for challenging infections and addressing the growing concern of antimicrobial resistance.

Biofilm Eradication

The compound's ability to inhibit and even eradicate bacterial biofilms is a critical advantage, offering new avenues for treating persistent infections and improving outcomes in healthcare settings.

Repurposing for Cancer Therapy

Recent studies suggest Nitroxoline's utility in cancer research, acting as a potential antiproliferative agent and influencing key signaling pathways, opening doors for novel therapeutic strategies.

Key Applications

Antibacterial Therapies

Leverage Nitroxoline's established antibacterial properties to combat urinary tract infections and other bacterial ailments, especially those caused by Gram-negative pathogens.

Anticancer Research

Investigate Nitroxoline's potential as an anticancer agent, exploring its antiproliferative effects and its role in drug repurposing initiatives for various cancer types.

Biofilm Management

Utilize Nitroxoline in strategies to combat bacterial biofilms, critical for managing chronic infections and preventing device-related complications.

Chemical Synthesis Intermediate

Employ Nitroxoline as a building block or intermediate in the synthesis of more complex pharmaceutical compounds and novel chemical entities.