(2R,3R,4S,5R)-2-(6-amino-9H-purin-9-yl)-5-((((1r,3S)-3-(2-(5-(tert-butyl)-1H-benzo[d]imidazol-2-yl)ethyl)cyclobutyl)(isopropyl)amino)methyl)tetrahydrofuran-3,4-diol CAS 1380288-87-8: A Potent DOT1L Inhibitor for Pharmaceutical Research
Discover Pinometostat (EPZ-5676), a highly selective DOT1L inhibitor crucial for MLL-rearranged leukemia research. Source this advanced pharmaceutical intermediate from a reliable manufacturer in China for your drug development needs. Get a quote and sample today!
Get a Quote & SampleUnlock Potential in Leukemia Treatment with Pinometostat
Pinometostat (EPZ-5676)
As a leading supplier of high-purity pharmaceutical intermediates, we offer Pinometostat (CAS 1380288-87-8), also known as EPZ-5676. This compound is a potent and highly selective inhibitor of DOT1L, a key target in the treatment of MLL-rearranged leukemia. Our commitment as a manufacturer in China ensures consistent quality and reliable supply for your research and development projects. Explore the benefits of sourcing your pharmaceutical raw materials from a trusted partner.
- Potent DOT1L Inhibition: Pinometostat selectively targets DOT1L with exceptional potency (IC50 of 0.8 nM), offering a significant advantage in therapeutic applications.
- MLL-Fusion Leukemia Treatment: This pharmaceutical intermediate has demonstrated efficacy in preclinical models by inhibiting H3K79 methylation and killing MLL-translocation-bearing leukemia cell lines.
- High Purity & Quality: As a dedicated manufacturer, we ensure our Pinometostat meets stringent purity standards, making it suitable for demanding research applications.
- Reliable Global Supply: We are a trusted supplier in China, committed to providing stable and consistent access to critical pharmaceutical raw materials for researchers worldwide.
Advantages of Sourcing Pinometostat from Our Facility
Advanced Synthesis Capabilities
Our state-of-the-art manufacturing facilities in China are equipped to produce complex pharmaceutical intermediates like Pinometostat (CAS 1380288-87-8) with high purity and consistency. Partner with a manufacturer dedicated to quality.
Expertise in Pharmaceutical Intermediates
Leveraging extensive experience in synthesizing intricate molecules, we provide EPZ-5676, a vital component for your drug discovery and development pipelines. Learn how our expertise can support your research goals.
Competitive Pricing and Timely Delivery
As a direct manufacturer and supplier, we offer competitive pricing for Pinometostat and ensure efficient logistics. Request a quote to understand our cost-effective solutions for bulk purchases.
Key Applications of Pinometostat (EPZ-5676)
Oncology Drug Development
Pinometostat is essential for researchers developing novel therapies targeting MLL-rearranged leukemias. Explore its potential to inhibit histone methyltransferase activity and its impact on cancer cell lines.
Pharmaceutical Research & Development
Utilize this high-quality pharmaceutical intermediate in preclinical and clinical studies to advance understanding of epigenetic regulation and targeted cancer treatments.
Histone Methyltransferase Inhibition Studies
Investigate the mechanisms of histone methylation and its role in disease pathology by using Pinometostat as a specific DOT1L inhibitor. Discover its application in molecular biology research.
Leukemia Targeted Therapy Research
As a key component in leukemia research, Pinometostat supports the development of targeted therapies that address specific genetic alterations like MLL translocations. Enquire about bulk purchase options.