Potassium Di-tert-butyl Phosphate: Your Key Pharmaceutical Intermediate for Enhanced Drug Bioavailability
Unlock the potential of your pharmaceutical formulations with Potassium di-tert-butyl phosphate. As a leading supplier in China, we provide this essential intermediate for developing advanced prodrugs that significantly boost API bioavailability, leading to more effective and easier drug administration.
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Potassium di-tert-butyl phosphate
We are a trusted supplier in China, offering Potassium di-tert-butyl phosphate (CAS 33494-80-3) a vital component in modern pharmaceutical development. Its primary role as a phosphorylating agent enables the creation of N-phosphonooxymethyl prodrugs, which are engineered to release active pharmaceutical ingredients (APIs) within the body, thereby enhancing bioavailability and improving drug delivery. This means drugs can be administered more conveniently, often as injectables, leading to better patient outcomes. Our commitment as a manufacturer in China ensures high purity and consistent supply for your critical projects.
- Facilitate the synthesis of N-phosphonooxymethyl prodrugs to enhance API bioavailability. This key capability allows for more effective drug delivery systems.
- Serve as a versatile catalyst in organic synthesis, particularly for cross-coupling reactions, enabling the efficient creation of complex molecular structures.
- Act as a critical intermediate for producing chloromethyl di-tert-butyl phosphate, a precursor essential for many phosphono-oxymethyl prodrugs.
- Enable the development of water-soluble azole antifungal compounds and other specialized pharmaceutical agents through nucleophilic substitution processes.
Advantages Offered by the Product
Enhanced Drug Efficacy
By improving API bioavailability through prodrug formulations, this compound contributes to more potent and effective therapeutic treatments, a critical aspect for pharmaceutical intermediate applications.
Improved Drug Administration
The enhanced bioavailability often allows for injectable formulations, simplifying drug administration for patients and healthcare providers, a key benefit in prodrug development technologies.
Synthetic Versatility
Its role as a catalyst in various organic synthesis reactions, including cross-coupling, makes it an invaluable tool for chemists working on complex molecular architectures, highlighting its use in advanced organic catalysis.
Key Applications
Pharmaceutical Synthesis
Essential for synthesizing N-phosphonooxymethyl prodrugs, crucial for enhancing API bioavailability and developing innovative drug delivery systems.
Organic Synthesis
Acts as a powerful catalyst in various organic reactions, including Buchwald-Hartwig, Heck, and Suzuki-Miyaura couplings, facilitating the synthesis of HIV attachment inhibitors.
Materials Science
Serves as a precursor for creating metal phosphate materials with specific crystal structures and spectral characteristics, valuable for specialty phosphate materials.
Antiviral Drug Development
Specifically utilized in the preparation of compounds like BMS-663068, showcasing its importance in the field of antiviral drug discovery.