Sodium Starch Glycolate: A Superior Tablet Disintegrant for Enhanced Drug Release
Unlock faster dissolution and improved bioavailability with our high-performance sodium starch glycolate.
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Sodium Starch Glycolate
Sodium Starch Glycolate is a critically important pharmaceutical excipient renowned for its efficacy as a tablet disintegrant. Produced by the chemical modification of starch, this sodium salt exhibits remarkable water absorption and swelling capabilities, which are fundamental to its role in promoting the rapid breakdown of tablets in the gastrointestinal tract. This characteristic ensures enhanced drug dissolution and subsequent absorption, directly impacting the therapeutic effectiveness of medications. Its application is vital for achieving optimal drug release profiles in various oral solid dosage forms, making it a cornerstone in modern pharmaceutical formulation science.
- Leverage the fast swelling disintegrant for tablets, ensuring quick tablet breakup for better drug absorption.
- Utilize the pharmaceutical excipient sodium starch glycolate for consistent and reliable tablet performance.
- Benefit from its ability to increase tablet hardness without affecting disintegration, a key advantage in formulation development.
- Explore the medicine grade sodium starch glycolate for its purity and suitability in pharmaceutical applications, ensuring patient safety.
Key Product Advantages
Exceptional Swelling Properties
Benefit from sodium starch glycolate's ability to absorb significant amounts of water, leading to rapid and efficient tablet disintegration, a crucial aspect for improving drug release profiles.
Cost-Effective Solution
The low cost and widespread availability of sodium starch glycolate make it an economically viable choice for pharmaceutical manufacturers looking to optimize production costs without compromising on quality.
Broad API Compatibility
This versatile excipient demonstrates excellent compatibility with a wide range of Active Pharmaceutical Ingredients (APIs), simplifying formulation design and reducing development time.
Key Applications
Tablet Formulations
As a premier tablet disintegrant, sodium starch glycolate ensures that tablets break down quickly upon contact with bodily fluids, facilitating efficient drug delivery.
Oral Solid Dosage Forms
Its application extends across various oral solid dosage forms, including tablets and capsules, where rapid dissolution is paramount for therapeutic success.
Enhancing Drug Release
The unique swelling and wicking action of sodium starch glycolate actively enhances the dissolution rate of poorly soluble drugs, improving their bioavailability.
Granulation Processes
It is highly effective when incorporated intragranularly and/or extragranularly in both dry and wet granulation processes, offering flexibility in manufacturing.