Tert-Butyl 3-Oxoazetidine-1-Carboxylate: A Key Pharmaceutical Intermediate
Unlock advanced drug synthesis with this essential heterocyclic building block.
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tert-Butyl 3-oxoazetidine-1-carboxylate
This compound is a vital intermediate, particularly in the synthesis of APIs like Baricitinib, a Janus kinase (JAK) inhibitor used for treating autoimmune diseases. Its stable yet reactive azetidine ring, protected by the tert-butoxycarbonyl (Boc) group, offers synthetic chemists a versatile scaffold for creating complex molecular architectures.
- Explore the synthesis of Baricitinib using this critical pharmaceutical intermediate, enabling advanced drug development.
- Understand the chemical properties of CAS 398489-26-4, including its appearance and stability for industrial applications.
- Leverage N-Boc-3-azetidinone as a building block in heterocyclic compound synthesis for novel therapeutic agents.
- Inquire about purchasing this key intermediate to streamline your drug discovery and development pipelines.
Key Advantages
High Purity and Reliability
Ensure consistency in your synthesis processes with a compound that offers a purity of ≥98.5%, crucial for pharmaceutical intermediate manufacturing.
Versatile Chemical Scaffold
The unique azetidine ring structure allows for diverse derivatization, making it a preferred choice for various heterocyclic compound synthesis projects.
Facilitates Complex Synthesis
Its inherent ring strain energy enables its use in demanding reactions, including high-temperature processes and nitration, vital for specific drug synthesis pathways.
Key Applications
Pharmaceutical Synthesis
Serves as a crucial intermediate for synthesizing active pharmaceutical ingredients (APIs), especially kinase inhibitors like Baricitinib, contributing to effective treatments for autoimmune diseases.
Heterocyclic Chemistry
A valuable building block for creating diverse heterocyclic compounds, opening avenues for new drug candidates and chemical entities in drug discovery.
Process Development
Utilized as a substrate in modern chemical processes like continuous flow hydrogenation, showcasing its adaptability in advanced manufacturing techniques.
Medicinal Chemistry Research
Its Boc-protected azetidine structure makes it highly valuable for researchers in medicinal chemistry, aiding in the exploration and development of novel therapeutic agents.