THZ1: A Potent and Selective CDK7 Inhibitor for Advanced Cancer Research
Discover the power of THZ1, a leading covalent inhibitor of CDK7, meticulously engineered for groundbreaking cancer research. Unlock new therapeutic avenues and gain a competitive edge by understanding its unique mechanisms and applications. Explore our offerings as a trusted manufacturer and supplier.
Get a Quote & SampleUnlocking New Frontiers in Cancer Treatment with THZ1
THZ1 - The Precision Inhibitor
As a premier manufacturer and supplier in China, we offer THZ1, a potent and selective CDK7 inhibitor (CAS: 1604810-83-4). Its unique ability to combine ATP-site and allosteric covalent binding allows for irreversible inhibition of CDK7, demonstrating significant anti-proliferative effects across diverse cancer cell lines. This makes it an invaluable asset for R&D, particularly in developing novel cancer therapies.
- Potent & Selective CDK7 Inhibition: Achieve precise research outcomes with an IC50 of 15.6nM, targeting aberrant transcription in cancer cells.
- Covalent Binding Mechanism: Our THZ1 supplier ensures high purity for reliable covalent binding, offering an advanced approach to disrupting cancer cell proliferation.
- Broad Anti-Proliferative Activity: Effectively inhibit transcription of critical proteins like MYC and PIM1, as evidenced by strong results in T-cell acute lymphoblastic leukaemia models.
- Therapeutic Advancement: Explore THZ1's role in overcoming drug resistance and enhancing targeted cancer therapies by understanding its unique interaction with CDK7.
Key Advantages of Sourcing THZ1 from Us
Unmatched Purity and Quality
As a leading THZ1 manufacturer, we guarantee >97% purity, ensuring reproducible and reliable results for your pharmaceutical intermediate research. Trust our supply chain for consistent quality.
Competitive Pricing and Availability
We offer competitive prices for THZ1, making cutting-edge research accessible. Connect with us for bulk inquiries and experience efficient procurement from our China-based facilities.
Expert Technical Support
Leverage our expertise as a specialized supplier of pharmaceutical intermediates. We provide detailed product data and support for your R&D needs, ensuring you can effectively buy THZ1 for your projects.
Applications of THZ1 in Pharmaceutical Research
Targeting Transcription Regulation
THZ1 is instrumental in studying and inhibiting abnormal transcription processes, crucial for understanding cancer development and metastasis. Its role in targeting super-enhancer-linked oncogenic transcription is a key area of research.
Oncology Drug Development
As a potent CDK7 inhibitor, THZ1 is vital for developing new targeted cancer therapies. Researchers utilize THZ1 to suppress STAT transcriptional activity and sensitize cancer cells to existing treatments.
Overcoming Drug Resistance
THZ1's ability to suppress adaptive responses to targeted therapies makes it a critical tool for researchers aiming to overcome drug resistance mechanisms in various cancers.
Biomarker and Pathway Analysis
Investigate the impact of CDK7 inhibition on gene expression, chromatin binding (e.g., STAT3), and protein transcription (e.g., MYC, PIM1) with high-purity THZ1 supplied by us.