Tubulysin A (TubA): Potent Anticancer Agent and ADC Payload Supplier

Discover Tubulysin A (TubA), a highly potent cytotoxic peptide from myxobacteria. With proven anti-microtubule and anti-mitotic activity, TubA is a key component in cutting-edge Antibody-Drug Conjugate (ADC) therapies. We are a reliable manufacturer and supplier, offering high-purity Tubulysin A for your research and development needs. Get a competitive quote and sample today to advance your oncology drug discovery.

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Key Advantages of Sourcing Tubulysin A

Exceptional Cytotoxicity

Tubulysin A exhibits picomolar potency, significantly outperforming many established chemotherapeutics, making it an ideal choice for targeted cancer therapies like ADCs.

Mechanism of Action: Tubulin Inhibition

By effectively inhibiting tubulin polymerization, Tubulysin A disrupts microtubule dynamics, leading to cell cycle arrest at the G2/M phase and inducing apoptosis in cancer cells.

Proven ADC Payload Potential

Its high potency and unique mechanism make Tubulysin A a valuable payload for Antibody-Drug Conjugates (ADCs), enabling targeted delivery to tumor sites for enhanced efficacy and reduced systemic toxicity.

Applications of Tubulysin A in Pharmaceutical R&D

Oncology Drug Development

Explore the use of Tubulysin A as a novel anticancer agent, targeting various cancer cell lines with its potent antiproliferative and cytotoxic effects.

Antibody-Drug Conjugate (ADC) Design

Utilize TubA as a high-potency payload for ADCs, offering a promising strategy for targeted cancer treatment and improved therapeutic outcomes.

Anti-angiogenic Therapies

Investigate Tubulysin A's potential in combating tumor growth by inhibiting angiogenesis, a critical process for tumor development and metastasis.

Preclinical and In Vitro Research

Source high-quality Tubulysin A for essential research, including cell cycle analysis, apoptosis studies, and mechanism of action investigations.