Exploring the Crucial Role of a Key Pharmaceutical Intermediate
Unveiling the significance of (3R,4R)-1-Benzyl-4-Methyl-3-Methylamino-Piperidine Dihydrochloride in advanced drug manufacturing.
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(3R,4R)-1-Benzyl-4-Methyl-3-Methylamino-Piperidine Dihydrochloride
This compound is a vital building block in the synthesis of Tofacitinib, a significant drug for treating autoimmune diseases. Its specific stereochemistry and high purity are essential for ensuring the efficacy and safety of the final pharmaceutical product, making it a cornerstone in modern drug development.
- Introduction to (3R,4R)-1-Benzyl-4-Methyl-3-Methylamino-Piperidine Dihydrochloride: This compound is recognized for its critical role in the synthesis of Tofacitinib, a JAK inhibitor used for autoimmune conditions.
- Chemical Properties for Synthesis: With a purity of at least 98% and a specific white powder appearance, its consistent physical and chemical attributes are crucial for reliable pharmaceutical production.
- Applications in Pharmaceutical Industry: The primary use of this intermediate is in the production of Tofacitinib and other Janus kinase (JAK) inhibitors, revolutionizing autoimmune disease treatment.
- Quality and Manufacturing Standards: As a key Tofacitinib intermediate, rigorous quality control and GMP standards are paramount to meet global pharmaceutical requirements.
Product Advantages
Purity and Consistency
Ensuring high purity of this crucial Tofacitinib intermediate guarantees the quality of downstream pharmaceutical products.
Stereochemical Precision
The precise (3R,4R) configuration is vital for the biological activity of the final drug, making it an indispensable component in JAK inhibitor synthesis.
Reliable Pharmaceutical Intermediate Supplier
Sourcing this compound from a trusted pharmaceutical intermediate supplier in China ensures timely delivery and adherence to stringent industry standards.
Key Applications
Tofacitinib Synthesis
The primary application of this compound is as a direct intermediate in the manufacturing of Tofacitinib, a key treatment for rheumatoid arthritis.
JAK Inhibitor Development
Beyond Tofacitinib, it serves as a building block for other Janus kinase (JAK) inhibitors, essential for modulating immune responses.
Pharmaceutical Research
This intermediate is crucial for ongoing research and development in medicinal chemistry, facilitating the discovery of new therapeutic agents.
Custom Synthesis Projects
For specialized drug development projects, this compound can be a key component in custom synthesis requirements.