Unlocking the Potential: Comprehensive Analysis of 6-(Trifluoromethyl)-1H-indole-2-carboxylic Acid in Organic Synthesis
Discover the critical properties, synthesis, and diverse applications of 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid, a vital intermediate for the pharmaceutical and agrochemical industries. Learn why this compound is essential for advanced organic synthesis.
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6-(Trifluoromethyl)-1H-indole-2-carboxylic acid
As a leading supplier in China, we offer 6-(Trifluoromethyl)-1H-indole-2-carboxylic acid, a crucial chemical intermediate known for its unique trifluoromethyl group attached to an indole backbone. This structure imparts distinct physical and chemical characteristics, making it a sought-after building block in various complex synthetic processes. Its high purity and consistent quality are assured by our advanced manufacturing practices, making us a reliable manufacturer in China.
- Explore the chemical intermediates for pharma: This compound is invaluable for the synthesis of pharmaceutical active ingredients, offering enhanced lipophilicity and metabolic stability essential for drug discovery.
- Understand 6-(trifluoromethyl)-1H-indole-2-carboxylic acid properties: With a density of 1.5±0.1 g/cm³, a high boiling point of 402.5±40.0 °C, and a flash point of 197.2±27.3 °C, it demonstrates remarkable thermal stability.
- Leverage indole-2-carboxylic acid applications: Its primary use as an intermediate in organic synthesis makes it a vital component for creating advanced molecules, particularly in the pharmaceutical and agrochemical sectors.
- Discover the significance of the trifluoromethyl group: This substituent enhances the acidity of the carboxylic acid and improves molecular framework stability, crucial for developing robust compounds with improved efficacy.
Key Advantages Offered
Enhanced Molecular Stability
The presence of the trifluoromethyl group in this indole-2-carboxylic acid derivative contributes significantly to the overall stability of synthesized molecules, a key factor in achieving reliable performance in pharmaceutical applications.
Versatile Synthetic Utility
As a pivotal intermediate for pharma, its adaptable structure allows for extensive modifications, enabling chemists to develop a wide array of novel compounds targeting specific biological pathways.
Optimized for Research
With an assay of ≥98.0%, this compound provides the high purity necessary for precise scientific research and development, ensuring accurate and reproducible results in complex organic synthesis endeavors.
Key Applications
Pharmaceutical Synthesis
A critical component in the development of new drug candidates, its indole scaffold and trifluoromethyl group offer unique properties for medicinal chemistry, directly contributing to advancements in pharmaceutical intermediate synthesis.
Agrochemical Development
Its stability and structural features make it a valuable precursor for creating novel agrochemicals, contributing to more effective and potentially safer crop protection solutions.
Advanced Organic Chemistry
Researchers in organic synthesis leverage this compound for its reactivity and the ability to introduce specific functionalities, aiding in the creation of complex molecular architectures.
HIV Research
Studies have identified indole-2-carboxylic acid derivatives as potential HIV-1 integrase strand transfer inhibitors, highlighting its significance in ongoing efforts to combat viral infections.