Verinurad: A Comprehensive Guide to URAT1 Inhibition for Gout and Hyperuricemia Management

Discover the science behind Verinurad, a key player in managing uric acid levels and treating gout.

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Key Advantages

Selective URAT1 Inhibition

Verinurad exhibits high affinity and selectivity for the human URAT1 transporter, ensuring targeted action with minimized off-target effects. This precision is key for effective uric acid management.

Therapeutic Potential for Gout

As a potent selective uric acid reabsorption inhibitor, Verinurad shows significant promise in clinical studies for the treatment of gout and hyperuricemia, aiming to reduce elevated serum uric acid levels.

Advanced Pharmaceutical Intermediate

With a purity often exceeding 98%, this compound serves as a critical pharmaceutical intermediate, supporting the development of novel therapies. Understanding hyperuricemia treatment options is vital.

Key Applications

Gout Treatment

Verinurad is being developed as a treatment for gout, a condition characterized by the buildup of uric acid crystals in the joints.

Hyperuricemia Management

Its ability to inhibit URAT1 makes it effective in lowering high levels of uric acid in the blood, a condition known as hyperuricemia.

Pharmaceutical Research

Serves as a vital research chemical for studies investigating URAT1 transporter function and developing new uricosuric agents.

Drug Discovery & Development

A key compound in the pipeline for new drug development targeting metabolic and inflammatory diseases.