Speciality Chemicals

1,3-Dimethylhexahydropyrimidin-2-one Hydrofluoride

  • CAS No.287966-55-6
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity 1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride complex designed for efficient nucleophilic fluorination in pharmaceutical and material science applications.

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Product Technical Details

Product Overview

1,3-Dimethylhexahydropyrimidin-2-one hydrofluoride, commonly recognized as DMPU-HF, represents a sophisticated fluorinating reagent engineered for advanced organic synthesis. This complex combines the polar aprotic solvent properties of DMPU with the reactivity of hydrogen fluoride, offering a safer and more manageable alternative to anhydrous HF in various chemical transformations. Our manufacturing process ensures exceptional stability and consistency, making it an indispensable tool for researchers and industrial chemists focused on introducing fluorine atoms into complex molecular structures.

As a leading provider in the fluorochemical sector, we prioritize safety and efficacy. This reagent is particularly valued for its ability to facilitate nucleophilic fluorination reactions under milder conditions compared to traditional methods. The unique solvation properties enhance the reactivity of fluoride ions, leading to higher yields and improved selectivity in the synthesis of pharmaceutical intermediates and advanced materials.

Technical Specifications

ParameterSpecification
Product Name1,3-Dimethylhexahydropyrimidin-2-one Hydrofluoride
CAS Number287966-55-6
Molecular FormulaC6H13FN2O
Molecular Weight148.18 g/mol
AppearanceColorless to pale yellow liquid
Purity>98.0% (GC)
Water Content<0.5%

Industrial Applications

  • Pharmaceutical Synthesis: Essential for producing fluorinated API intermediates with enhanced metabolic stability.
  • Agrochemical Development: Utilized in the creation of novel pesticides requiring specific fluorine substitution patterns.
  • New Material Science: Supports the development of fluoropolymers and electronic chemicals with superior performance characteristics.
  • Organic Fluorination: Acts as a reliable source of nucleophilic fluoride for diverse substitution reactions.

Quality Assurance and Safety

Our commitment to quality is reflected in our comprehensive testing protocols. Every batch undergoes rigorous analysis using gas chromatography and Karl Fischer titration to confirm purity and moisture levels. We provide a complete Certificate of Analysis (COA) with each shipment, ensuring transparency and compliance with international standards. Proper handling is crucial; while safer than anhydrous HF, this product should be managed in a well-ventilated environment with appropriate personal protective equipment. We offer global shipping solutions with specialized packaging to maintain product integrity during transit, supporting our partners in maintaining uninterrupted production schedules.