Speciality Chemicals

Diethyl (difluoromethyl)phosphonate

  • CAS No.1478-53-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Diethyl (difluoromethyl)phosphonate (CAS 1478-53-1) is a specialized fluorinated reagent designed for pharmaceutical and agrochemical synthesis.

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Product Technical Details

Product Overview

Diethyl (difluoromethyl)phosphonate is a highly valued organofluorine compound widely recognized for its utility in modern organic synthesis. As a key fluorinated building block, this reagent facilitates the introduction of the difluoromethyl group into complex molecular structures. The difluoromethyl moiety is increasingly significant in medicinal chemistry and agrochemical development due to its unique ability to modulate lipophilicity, metabolic stability, and bioavailability without significantly altering the steric profile of the parent molecule. Our supply ensures consistent quality for research and industrial scale applications.

Key Specifications

We adhere to strict quality control protocols to guarantee the purity and reliability of every batch. The following technical parameters define the standard grade available for immediate shipment. Custom specifications may be discussed upon request for large-scale manufacturing needs.

PropertySpecification
CAS Number1478-53-1
Molecular FormulaC5H11F2O3P
Molecular Weight188.11 g/mol
AppearanceColorless to pale yellow liquid
Density1.181 g/cm3
Boiling Point179.2ºC at 760mmHg
Flash Point62.2ºC
Refractive Indexn20/D 1.388 (lit.)
Vapor Pressure1.29mmHg at 25ºC

Industrial Applications

This fluorinated phosphonate serves as a critical intermediate in the synthesis of novel pharmaceutical agents, particularly where metabolic stability is required. It is extensively used in the development of new pesticides, contributing to the creation of more effective and environmentally stable agrochemical solutions. Furthermore, it plays a vital role in the manufacture of advanced new materials, where fluorine content enhances performance characteristics. Researchers utilize this compound for diverse organic transformations, leveraging its reactivity to construct complex fluorinated architectures essential for next-generation technologies.

Quality Assurance and Supply Chain

Our company is dedicated to establishing a comprehensive fluorochemical products and technology platform. We provide customers with convenient one-stop services ranging from raw material procurement to final product delivery. Our integrated industrial chain covers fluorination technology research and development, production, storage, and rigorous quality control. Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with stated specifications. We strive to maintain a robust supply chain that ensures timely delivery and consistent product performance for global partners.

Storage and Handling

Proper storage is essential to maintain the integrity of Diethyl (difluoromethyl)phosphonate. The material should be kept in a cool, dry, and well-ventilated area away from incompatible substances. Containers must be tightly closed when not in use to prevent moisture uptake or contamination. Given the flash point of 62.2ºC, standard safety precautions for flammable liquids should be observed during handling and transportation. Always refer to the Safety Data Sheet (SDS) for detailed hazard information and emergency procedures before use.