Speciality Chemicals

Diethylaminosulfur Trifluoride

  • CAS No.38078-09-0
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High-purity Diethylaminosulfur Trifluoride (DAST) is a premier fluorinating reagent for organofluorine compound synthesis. Ideal for pharmaceutical R&D and new material development with strict quality control.

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Product Technical Details

Product Overview

Diethylaminosulfur Trifluoride, commonly known as DAST, represents a critical advancement in modern organofluorine chemistry. As a highly efficient fluorinating reagent, it enables the precise introduction of fluorine atoms into organic molecules, a process essential for enhancing the metabolic stability and bioavailability of pharmaceutical compounds. Our facility specializes in the production of this specialized chemical, ensuring that every batch meets rigorous international standards for purity and performance. This product is indispensable for researchers and industrial manufacturers focused on developing next-generation pharmaceuticals, agrochemicals, and advanced functional materials.

The compound functions primarily by converting alcohols and carbonyl groups into their corresponding fluorinated analogs. This transformation is vital in medicinal chemistry, where fluorine substitution often leads to improved drug potency and resistance to enzymatic degradation. Our commitment to excellence means we provide a reliable supply chain for this sensitive reagent, supporting both large-scale industrial processes and precise laboratory-scale experiments.

Technical Specifications

ParameterSpecification
CAS Number38078-09-0
Molecular FormulaC4H10F3NS
Molecular Weight161.19 g/mol
AppearanceColorless oil (may turn orange upon aging)
Density1.22 g/mL at 25 °C
Boiling Point30-32 °C at 3 mm Hg
Refractive Index1.41-1.416
Flash Point75 °F
Water SolubilityDecomposes

Industrial Applications

The primary application of Diethylaminosulfur Trifluoride lies in the synthesis of organofluorine compounds. In the pharmaceutical sector, it is utilized to create fluorinated intermediates that serve as building blocks for complex active pharmaceutical ingredients (APIs). The presence of fluorine can significantly alter the electronic and steric properties of a molecule, making DAST a key tool in drug discovery pipelines. Additionally, this reagent is employed in the development of new pesticides, where fluorination enhances environmental stability and efficacy.

Beyond life sciences, our fluorinating agents support the new materials industry. Researchers use this chemistry to develop polymers and coatings with superior resistance to heat, chemicals, and weathering. Whether for academic research or commercial production, our product provides the consistency required for reproducible results. We understand the nuances of fluorine chemistry and tailor our purification processes to minimize impurities that could interfere with sensitive synthetic routes.

Safety and Storage Guidelines

Handling Diethylaminosulfur Trifluoride requires strict adherence to safety protocols due to its reactivity. The compound is stable under normal temperatures and pressures but combines vigorously or explosively with water. Therefore, it must be stored in a cool, dry environment, specifically between 2-8°C, to maintain integrity and prevent decomposition. Proper personal protective equipment, including gloves and eye protection, is mandatory during handling. Our packaging is designed to ensure safe transport, minimizing exposure to moisture and air.

Quality Assurance and Supply

Our company is dedicated to establishing a complete fluorochemical products and technology platform. We provide convenient one-stop services for customers seeking reliable fluorinated reagents. Our products are widely used in the manufacture of new materials, pharmaceutical research, and pesticide development. We strive to build a complete industrial chain covering raw material procurement, technology research, production, storage, and quality control. Every shipment is accompanied by a Certificate of Analysis (COA) to verify compliance with specified parameters. As a global manufacturer, we offer competitive bulk pricing and ensure timely delivery to support your production schedules.