Speciality Chemicals

Dimethyl Difluoromalonate

  • CAS No.379-95-3
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Dimethyl Difluoromalonate for advanced organic synthesis. Reliable bulk supply from a dedicated fluorine technology platform.

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Product Technical Details

Product Overview

Dimethyl Difluoromalonate is a specialized fluorinated building block designed for complex organic synthesis and medicinal chemistry applications. As a key intermediate in the introduction of difluoro methylene groups, this compound offers exceptional stability and reactivity profiles required for modern pharmaceutical and agrochemical development. Our formulation ensures high chemical purity, making it an ideal candidate for researchers and industrial manufacturers seeking reliable fluorinated reagents.

The incorporation of fluorine atoms into organic molecules often enhances metabolic stability, lipophilicity, and bioavailability. This product serves as a critical precursor in the synthesis of novel active pharmaceutical ingredients (APIs) and high-performance materials. By utilizing our premium grade Dimethyl Difluoromalonate, chemists can achieve greater precision in constructing fluorinated scaffolds essential for next-generation therapeutics.

Technical Specifications

ParameterValue
Product NameDimethyl Difluoromalonate
CAS Number379-95-3
Molecular FormulaC5H6F2O4
Molecular Weight168.10 g/mol
Density1.303 g/cm3
Boiling Point134.4ºC at 760 mmHg
Flash Point35ºC
Refractive Index1.368

Industrial Applications

This fluorinated ester is extensively utilized across multiple high-value sectors. In pharmaceutical research and development, it acts as a versatile synthon for creating fluorinated heterocycles and amino acid derivatives. The difluoro motif is increasingly recognized for its ability to modulate protein binding interactions, making this reagent indispensable for drug discovery programs targeting metabolic disorders and oncology.

Beyond healthcare, the compound finds significant application in the development of new pesticides and agrochemicals. Fluorination often improves the environmental stability and efficacy of crop protection agents. Additionally, our clients in the new materials sector leverage this building block for synthesizing advanced polymers and liquid crystals with enhanced thermal and chemical resistance properties.

Quality Assurance And Supply

Our company is committed to establishing a complete fluorochemical products and technology platform to provide customers with convenient one-stop services. We maintain strict quality control protocols throughout the manufacturing process, ensuring every batch meets rigorous international standards. Each shipment is accompanied by a comprehensive Certificate of Analysis (COA) to verify identity and purity.

  • Consistent industrial purity levels for reproducible synthesis results.
  • Scalable production capacity to support bulk procurement needs.
  • Integrated supply chain from raw material procurement to final product storage.
  • Dedicated technical support for application development and process optimization.

Shanghai Fluorine Technology strives to build a complete industrial chain covering fluorine-containing raw material procurement, fluorination technology research and development, and product application. We invite global partners to collaborate with us for secure, high-quality supply solutions tailored to your specific chemical synthesis requirements.