N-Methyl-bis(trifluoroacetamide)
- CAS No.685-27-8
- GradeIndustrial / Pharmaceutical
- Availability● In Stock
High-purity N-Methyl-bis(trifluoroacetamide) (MBTFA) is a versatile trifluoroacetylating agent designed for pharmaceutical R&D and analytical derivatization.
Request a Quote & Full COAProduct Technical Details
Product Overview
N-Methyl-bis(trifluoroacetamide), commonly known as MBTFA, stands as a premier fluorinated reagent within the landscape of modern organic synthesis and analytical chemistry. This specialized chemical compound serves as a potent trifluoroacetylating agent, engineered to facilitate complex molecular transformations with high efficiency. As a key component in the fluorine chemistry portfolio, it enables researchers and industrial manufacturers to introduce trifluoroacetyl groups into various organic substrates, thereby enhancing volatility and detectability for gas chromatography mass spectrometry (GC/MS) analysis.
Our commitment to excellence ensures that every batch of N-Methyl-bis(trifluoroacetamide) meets rigorous international standards for purity and performance. Produced on a dedicated fluorochemical technology platform, this reagent supports critical workflows in pharmaceutical development, new material science, and pesticide research. The strategic incorporation of fluorine atoms often improves the metabolic stability and bioavailability of drug candidates, making MBTFA an indispensable tool for medicinal chemists aiming to optimize lead compounds.
Technical Specifications
| Parameter | Specification |
|---|---|
| Product Name | N-Methyl-bis(trifluoroacetamide) |
| CAS Number | 685-27-8 |
| Molecular Formula | C5H3F6NO2 |
| Molecular Weight | 223.07 g/mol |
| Appearance | Transparent colorless liquid |
| Density | 1.547 g/mL at 25°C |
| Boiling Point | 121-122°C |
| Flash Point | 42°C |
| Refractive Index | n20/D 1.346 |
| Storage Temperature | 2-8°C |
Industrial Applications
- Analytical Derivatization: Primarily used to derivatize alcohols, amines, phenols, and carboxylic acids, rendering them volatile enough for precise GC/MS detection.
- Pharmaceutical Synthesis: Acts as a critical building block in the synthesis of fluorinated active pharmaceutical ingredients (APIs) to enhance drug potency.
- New Material Development: Utilized in the creation of advanced fluorinated polymers and specialty materials with unique thermal and chemical resistance.
- Pesticide R&D: Supports the development of next-generation agrochemicals by enabling specific structural modifications.
- Quality Control: Essential reagent for laboratories requiring high-fidelity results in trace analysis and impurity profiling.
Quality Assurance and Storage
Maintaining the integrity of fluorinated reagents requires strict adherence to storage and handling protocols. N-Methyl-bis(trifluoroacetamide) should be stored in a cool, dry environment between 2-8°C to prevent degradation and moisture absorption. Our manufacturing process includes comprehensive quality control measures, ensuring that each shipment is accompanied by a Certificate of Analysis (COA) verifying purity levels and physical constants. We prioritize safety and compliance, providing detailed safety data sheets (SDS) with every order to ensure safe handling in your facility.
As a global manufacturer, we understand the need for reliable supply chains. Our fluorochemical platform integrates raw material procurement, technology development, and production under one roof, guaranteeing consistency and competitive bulk pricing. Whether for small-scale laboratory research or large-scale industrial production, our team is dedicated to providing technical support and logistics solutions that meet your specific project timelines.
