Speciality Chemicals

Tetrabutylammonium Fluoride

  • CAS No.22206-57-1
  • GradeIndustrial / Pharmaceutical
  • Availability● In Stock

High purity Tetrabutylammonium Fluoride (TBAF) reagent for efficient desilylation and organic synthesis applications. Available in bulk with full documentation.

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Product Technical Details

Product Overview

Tetrabutylammonium Fluoride, commonly abbreviated as TBAF, is a premier quaternary ammonium salt widely recognized for its exceptional utility in organic synthesis and pharmaceutical research. As a potent source of naked fluoride ions, this chemical serves as a critical reagent for the cleavage of silyl ether protecting groups, enabling precise molecular modifications during complex synthesis routes. Our manufacturing process ensures high industrial purity, making it an ideal choice for demanding applications in new material development and fine chemical production.

We understand the critical nature of reagent quality in research and development. Therefore, our Tetrabutylammonium Fluoride is produced under strict quality control protocols to guarantee consistency across batches. Whether utilized in academic laboratories or large-scale industrial processes, this product delivers reliable performance and reproducibility.

Key Specifications

PropertySpecification
CAS Number22206-57-1
Molecular FormulaC16H36FN
Molecular Weight261.46 g/mol
AppearanceWhite to off-white powder
Density0.953 g/mL at 25°C
Melting Point62-63°C
Storage Conditions2-8°C, keep dry

Industrial Applications

The primary application of Tetrabutylammonium Fluoride lies in its ability to facilitate desilylation reactions. In pharmaceutical R&D, it is extensively used to remove silyl protecting groups from alcohols and amines without affecting other sensitive functional groups. This selectivity is crucial for the synthesis of advanced therapeutic intermediates and active pharmaceutical ingredients.

Beyond pharmaceuticals, this specialty chemical plays a vital role in the development of new materials. It is employed in the synthesis of fluorinated compounds, polymers, and specialized coatings where precise fluoride introduction is required. Our company supports the entire industrial chain, from raw material procurement to final product application, ensuring that customers receive a comprehensive solution for their fluorochemical needs.

Quality Assurance and Handling

As a global manufacturer, we prioritize safety and quality. Each batch of Tetrabutylammonium Fluoride undergoes rigorous testing to verify purity and composition. A Certificate of Analysis (COA) is provided with every shipment to confirm compliance with specified standards. Proper storage is essential to maintain product integrity; we recommend keeping the material in a cool, dry environment between 2-8°C to prevent hydration changes or degradation.

Our commitment extends to providing convenient one-stop services for all fluorochemical products. From fluorinated reagents to building blocks, we strive to support innovation in chemistry through reliable supply chains and technical expertise. For bulk pricing inquiries or technical support regarding synthesis routes, our team is ready to assist you in optimizing your production processes.